Rudy Lab Contacts People
People
Current Lab Members | Photo Album | Former Lab Members | Collaborators

Yoram Rudy Current Laboratory Members

Front Row: Ashwin Mohan, Ramya Vijayakumar, Smiruthi Ramasubramanian, Junjie Zhang (alumnus)
Back Row: Christopher Andrews, Yoram Rudy, Jiajing Xu, Huyen (Gwen) Nguyen, Maya Bera

Dr. Yoram Rudy
Research Scientist
Postdoctoral Research Associate
Graduate Students
Clinical Faculty, Staff & Fellows
Administrative Staff

Yoram Rudy, Ph.D., F.A.H.A.

(Case Western Reserve University, 1978); The Fred Saigh Distinguished Professor of Engineering; Professor of Biomedical Engineering, Cell Biology & Physiology, Medicine, Radiology, and Pediatrics; Director of the Cardiac Bioelectricity and Arrhythmia Center (CBAC)

Full CV:
(Flip .pdf )

Short NIH Biosketch:
(pdf )

Websites:
http://rudylab.wustl.edu
http://cbac.wustl.edu

Email: rudy@wustl.edu
Tel: (314) 935-8160

Our research aims at understanding the mechanisms that underlie normal and abnormal rhythms of the heart at various levels, from the molecular (ion channel) and cellular to the whole heart. We are also developing a novel noninvasive imaging modality (Electrocardiographic Imaging, ECGI) for the diagnosis and guided therapy of cardiac arrhythmias.

For details, please see Research

Yoram Rudy
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Research Scientist

Ashwin Mohan
Ph.D. in Electrical and Computer Engineering, University of Missouri, 2009

Research Scientist

Email: amohan22@wustl.edu
Tel: (314) 935-8163

My research is focused on altered rate dependence of action potential repolarization and its role in inducing arrhythmias in the remodeled epicardium post infarction.

Ashwin Mohan Washington University
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Postdoctoral Research Associate

Ramya Vijayakumar
M.S. in Biomedical Engineering, Rutgers, The State University of New Jersey, 2007
Ph.D. in Biomedical Engineering, Washington University in St. Louis, 2016

Email: rvijayak@wustl.edu
Tel: (314) 935-8163

My research: I am interested in studying the clinical applications of Electrocardiographic Imaging.

Ramya Vijayakumar
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Graduate Students

Christopher Andrews
B.S. in Biomedical Engineering, Washington University in St. Louis, 2007

Ph.D. Graduate Student

Email: candrews@wustl.edu
Tel: (314) 935-8163

My research is focused on the electrical-mechanical relationship in heart failure patients and its alteration by cardiac resynchronization therapy (CRT).

Chris Andrews Washington University Bioengineering
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Smiruthi Ramasubramanian
B.A. in Biomedical Engineering, Texas A & M, 2008

Ph.D. Graduate Student

Email: sramasubramanian@wustl.edu
Tel: (314) 935-8163

My research: Building and using the computational structural model (based on experimental data) of the cardiac IKs ion channel to study the structure-function correlation, mutation effects and the beta-adrenergic modulation from the perspective of whole cell currents and action potentials.

Smiruthi Ramasubramanian
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Jiajing Xu
B.Eng. in Biomedical Engineering, Chu Kochen Honors College,
Zhejiang University, China, 2008

Ph.D. Graduate Student

Email: jxu@go.wustl.edu
Tel: (314) 935-8163

My research: I am interested in modeling molecular mechanisms of activation and inactivation processes for specific ion channels, for example, the IKs channel, involved in shaping action potentials of the cardiac cell.

Jiajing Xu Washington University St. Louis
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Clinical Faculty, Staff & Fellows

Daniel H. Cooper, M.D.
Med school: Loyola University Chicago Stritch School of Medicine
Residency: Internal Medicine, Barnes-Jewish Hospital
Chief Residency: Internal Medicine, Barnes-Jewish Hospital

Assistant Professor of Medicine, School of Medicine, Cardiovascular Division

Email: cooperdh@wustl.edu
Tel: (314) 747-8494
Website 

Research interests: My current collaboration with Dr. Rudy’s lab looking at the differences in electrophysiologic substrate in ischemic cardiomyopathy patients with and without clinical ventricular arrhythmias is particularly exciting. We are utilizing ECGi to noninvasively characterize patients who have required ICD therapy to terminate VT and comparing them to patients who have never received ICD therapy despite being > 4 years since implant and having, on the surface, similar clinical characteristics. Preliminary results suggest patients with VT tend to have larger areas of abnormal electrophysiologic substrate and have a greater prevalence of electrogram characteristics reflective of scar heterogeneity. A better understanding of what makes these patients different will aid in our ability to risk stratify our patients and could contribute to decisions regarding ablative therapies in the future.

In the next few years, I hope to quickly build a successful, busy clinical practice. I hope to offer my patients the opportunity to participate in research that will be geared towards advancing our understanding of their ailment. Through my collaboration with scientists in CBAC I hope to contribute to cutting edge research that will push the science forward and provide us the insight and/or technology not yet available to improve outcomes for our patients.

Daniel H. Cooper
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Phillip S. Cuculich, M.D.
Med school: Vanderbilt University
Residency: Northwestern University
Chief Residency: Northwestern University

Associate Professor of Medicine, School of Medicine, Cardiovascular Division

Email: pcuculic@wustl.edu
Tel: (314) 454-7698
Website

Clinical interests: Arrhythmias, sudden cardiac death, atrial fibrillation, ventricular tachycardia. Under the guidance of the electrophysiology division, I was involved in reporting our experience demonstrating an overall poor prognosis for patients with chronic kidney disease despite ICD therapy for the primary prevention of sudden death. 

Research interests: Under the mentorship of  Dr. Yoram Rudy, we have applied a novel noninvasive electrocardiographic imaging system (ECGI) to create three-dimensional electroanatomic maps of various arrhythmias, with a focus on ventricular tachycardia and atrial fibrillation. Through better understanding of basic mechanisms of arrhythmia, the ultimate clinical application of this research is to tailor specific therapies for individual patients based on the unique electrophysiologic characteristics of each arrhythmia.

Phillip S. Cuculich
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Jennifer N. A. Silva, M.D.
Med school: St. George's University School of Medicine, Grenada, West Indies
Residency: Pediatrics, Miami Children's Hospital
Fellowship: Pediatric Cardiology, Washington University

Fellowship: Pediatric Electrophysiology, Children's Hospital Boston

Assistant Professor of Pediatrics, School of Medicine, Pediatrics Cardiology

Email: jennifersilva@wustl.edu
Tel: (314) 454-2544
Website

Clinical interests:

  • Clinical Electrophysiology/Arrhythmias
  • Inherited Channelopathies
  • Transcatheter ablations
  • Pacemakers/Defibrillators
  • Heart Failure and Cardiac Resynchronization Therapy
  • Sudden Cardiac Death

Research interests:

  • Clinical Applications of Noninvasive Electrocardiographic Imaging (ECGI)
  • Pediatric Cardiac Resynchronization Therapy

Jennifer Silva
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Matthew Schill, M.D.
Med school: Washington University School of Medicine
Residency: General Surgery, Department of Surgery, Washington University School of Medicine
Fellowship: Cardiothoracic Surgery, Washington University School of Medicine

Research Fellow, General Surgery, Washington University School of Medicine

Email: schillm@wustl.edu
Tel: (314) 454-7194
Website

Matthew Schill
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Administrative Staff

Maya Bera

Senior Computer Specialist and Webmaster for rudylab website

Email: maya_bera@wustl.edu
Tel: (314) 935-8163

Job Responsibilities: Install, maintain and administer Linux/Windows clusters. Webmaster for the lab research website. Provide Linux support and programming support for the computational research. Provide support for the ECGI research.

Maya Bera
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Huyen (Gwen) Nguyen
B.S. Botany, University of Wisconsin-Madison

CBAC Coordinator and Webmaster for CBAC and rudylab websites

Email: nguyeng@wustl.edu
Tel: (314) 935-8163

Job Responsibilities: I am the administrator for the CBAC and Rudy Lab. I am responsible for CBAC programming and events. I am also responsible for grants, budgets, and all CBAC publications which includes newsletters and brochures.

Bio: I attended the University of Wisconsin – Madison and graduated with a B.S. degree in Botany.  Upon graduation, I worked for the United States Department of Agriculture’s National Arboretum in Washington, D.C.

From 2007 to 2012, I was the Assistant to the Chair in the Department of Art at U.W. – Madison where I was responsible for assisting the Department Chair in a wide range of activities, including alumni relations, external relations, personnel, and programming in addition to putting together grants and fundraising to make all of these activities happen.

Huyen (Gwen) Nguyen
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