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To develop computational biology tools for the study of arrhythmia mechanisms at all levels of the cardiac system (ion- channel, cardiac cell, multicellular tissue, whole-heart). |
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To use these tools, in combination with experimental data, to elucidate the mechanisms and simulate the arrhythmogenic consequences of hereditary (genetic) and acquired (environmental) cardiac disease. |
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To simulate the effects of therapeutic interventions (drugs, genetic modification, pacing) on cardiac arrhythmias in an effort to help develop better strategies for therapy. |
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To provide training in the application of quantitative approaches to the research of cardiac arrhythmias and to the design/realization of novel diagnostic tools. |
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To provide an environment for mechanism-based diagnosis of cardiac arrhythmias. |
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