To develop computational biology tools for the study of arrhythmia mechanisms at all levels of the cardiac system (ion-
channel, cardiac cell, multicellular tissue, whole-heart).
To use these tools, in combination with experimental data, to elucidate the mechanisms and simulate the arrhythmogenic
consequences of hereditary (genetic) and acquired (environmental) cardiac disease.
To simulate the effects of therapeutic interventions (drugs, genetic modification, pacing) on cardiac arrhythmias in an effort
to help develop better strategies for therapy.
To provide training in the application of quantitative approaches to the research of cardiac arrhythmias and to the
design/realization of novel diagnostic tools.
To provide an environment for mechanism-based diagnosis of cardiac arrhythmias.

Return to Basic Mechanisms of Excitation and Arrhythmias

Copyright © 2005-2008 Yoram Rudy, Ph.D. All Rights Reserved.  •  Contact Webmaster