Chronological List of All Rudy Lab Publications

(Link to MyNCBI Bibiliography)

2021

Y. Rudy. Noninvasive Mapping of Repolarization With Electrocardiographic Imaging. J Am Heart Assoc. 2021 May 4;10(9):e021396. doi: 10.1161/JAHA.121.021396. Epub 2021 Apr 21. PMID: 33880937; PMCID: PMC8200737.

2020

Y. Rudy. In Silico Pipeline for Drug Cardiotoxicity Assessment. Circ Res. 2020 Apr 10;126(8):965-967. doi: 10.1161/CIRCRESAHA.120.316901. Epub 2020 Apr 9. PMID: 32271685

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2019

C. Andrews, B.P. Cupps, M.K. Pasque, Y. Rudy. Electromechanics of the Normal Human Heart In Situ. Circ Arrhythm Electrophysiol. 2019 Nov;12(11):e007484. PMID: 31698936

M. Orini, A.J. Graham, A. Martinez-Naharro, C.M. Andrews, A. de Marvao , B. Statton , S. A. Cook, D.P. O’Regan, P.N. Hawkins, Y. Rudy, M. Fontana, P.D. Lambiase. Noninvasive Mapping of the Electrophysiological Substrate in Cardiac Amyloidosis and Its Relationship to Structural Abnormalities. J Am Heart Assoc. 2019 Sep 17;8(18):e012097. doi: 10.1161/JAHA.119.012097. Epub 2019 Sep 8. PMCID: PMC31496332

C.G. Robinson, P.P. Samson, K.M.S. Moore, G. D. Hugo, N. Knutson, S. Mutic, S.M. Goddu, A. Lang, D.H. Cooper, M. Faddis, A. Noheria, T.W. Smith, P.K. Woodard, R.J. Gropler, D.E. Hallahan, Y. Rudy, P.S. Cuculich. Phase I/II Trial of Electrophysiology-Guided Noninvasive Cardiac Radioablation for Ventricular Tachycardia. Circulation. 2019 Jan 15;139(3):313-321. doi: 10.1161/CIRCULATIONAHA.118.038261. PMCID: PMC6331281 (Recipient of the 2019 James T. Willerson award in Clinical Science for the best clinical paper published in Circulation in the past 12 months)

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2018

J. Xu, Y. Rudy. Effects of β-subunit on gating of a potassium ion channel: Molecular simulations of cardiac IKs activation. J Mol Cell Cardiol. 2018 Nov;124:35-44. doi: 10.1016/j.yjmcc.2018.10.003. Epub 2018 Oct 4. PMCID: PMC6265052

S. Ramasubramanian, Y. Rudy. The Structural Basis of IKs Ion-Channel Activation: Mechanistic Insights from Molecular Simulations. Biophys J. 2018 Jun;114(11):2584-2594. doi: 10.1016/j.bpj.2018.04.023. PMCID: PMC29874609

Y. Rudy. Role for Electrocardiographic Imaging in Cardiac Resynchronization Therapy? Heart Rhythm. 2018 Jul;15(7):1070-1071. doi: 10.1016/j.hrthm.2018.03.011. Epub 2018 Mar 9. (Editorial Commentary). PMID: 29530831

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2017

P.S. Cuculich, M.R. Schill, R. Kashani, S. Mutic, A. Lang, D. Cooper, M. Faddis, M. Gleva, A. Noheria, T.W. Smith, D. Hallahan, Y. Rudy, C.G. Robinson. Noninvasive Cardiac Radiation for Ablation of Ventricular Tachycardia. N Engl J Med. 2017 Dec; 377:2325-2336. PMCID: PMC5764179

H.C. Lee, Y. Rudy, H. Liang, C.C. Chen, C.H. Luo, S.H. Sheu, J. Cui. Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets – Insights from Modeling. J Med Biol Eng. 2017 Oct;37(5):780-789. PMCID: PMC5714284

C.M. Andrews, N.T. Srinivasan, S. Rosmini, H. Bulluck, M. Orini, S. Jenkins, A. Pantazis, W.J. McKenna, J. Moon, P.D. Lambiase, Y. Rudy. The Electrical and Structural Substrate of Arrhythmogenic Right Ventricular Cardiomyopathy Determined Using Noninvasive Electrocardiographic Imaging and Late Gadolinium Magnetic Resonance Imaging.  Circ Arrhythm Electrophysiol. 2017 Jul;10(7). Editor’s Pick. PMCID: 5533087

J. Zhang, M. Hocini, M. Strom, P.S. Cuculich, D.H. Cooper, F. Sacher, M. Haïssaguerre, Y. Rudy. The Electrophysiological Substrate of Early Repolarization Syndrome: Noninvasive Mapping in Patients. JACC: Clinical Electrophysiology. Mar 2017, 335; DOI: 10.1016/j.jacep.2016.12.017. PMCID: PMC5675574

Y. Rudy. Noninvasive ECG imaging (ECGI): Mapping the arrhythmic substrate of the human heart. International Journal of Cardiology. Feb 2017, 237 (13-14). PMCID: PMC5441950

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2016

R. Vijayakumar, S.K Vasireddi, P.S. Cuculich, M.N. Faddis, Y. Rudy. Methodology Considerations in Phase Mapping of Human Cardiac Arrhythmias. Circ Arrhythm Electrophysiol. 2016 Nov;9(11). pii: e004409. PMCID: PMC5137810

J. Zhang, D.H. Cooper, K.A. Desouza, P.S. Cuculich, P.K. Woodard, T. W. Smith, Y. Rudy. Electrophysiologic Scar Substrate in Relation to VT: Noninvasive High-Resolution Mapping and Risk Assessment with ECGI. Pacing Clin Electrophysiol. 2016 Aug;39(8):781-91. doi: 10.1111/pace.12882. Epub 2016 Jun 6. PMCID: PMC4970912

A. Nekouzadeh, Y. Rudy. Conformational changes of an ion-channel during gating and emerging electrophysiologic properties: Application of a computational approach to cardiac Kv7.1. Prog Biophys Mol Biol. 2016 Jan;120(1-3):18-27. 2015.12.014. Epub 2015 Dec 30. PMID: 26743208; PMCID: PMC4955398

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2015

J. Zhang, F. Sacher, K. Hoffmayer, T. O’Hara, M. Strom, P.S. Cuculich, J. Silva, D. Cooper, M. Faddis, M. Hocini, M. Haissaguerre, M. Scheinman, Y. Rudy. Cardiac Electrophysiologic Substrate Underlying the ECG Phenotype and Electrogram Abnormalities in Brugada Syndrome Patients. Circulation. 2015 Jun 2;131(22):1950-9. PMCID: PMC4452400

Silva JN. Pediatric Electrocardiographic Imaging (ECGI) Applications. Card Electrophysiol Clin. 2015 Mar 1;7(1):135-152. PMCID: PMC4337427

Y. Rudy, B.D. Lindsay. Electrocardiographic Imaging of Heart Rhythm Disorders: From Bench to Bedside. Card Electrophysiol Clin. 2015 Mar 1;7(1):17-35. PMCID: PMC4337422

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2014

R. Vijayakumar, J.N. Silva, K.A. Desouza, R.L. Abraham, M. Strom, F. Sachar, G.F. Van Hare, M. Haissaguerre, D.M. Roden, Y. RudyElectrophysiologic Substrate in Congenital Long QT Syndrome: Noninvasive Mapping with Electrocardiographic Imaging (ECGI). Circulation 2014;130:1936-1943. PMCID: PMC4245321

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2013

K. A. Desouza, S. Joseph, P.S. Cuculich, G.A. Ewald, Y. Rudy.  Noninvasive mapping of ventricular activation in patients with transplanted hearts. J Electrocardiol. 2013 Nov-Dec;46(6):698-701. PMCID: PMC3800274

K. A. Desouza, S. Joseph, Y. RudyNoninvasive electrophysiologic imaging of acute rejection in a transplanted heart. Europace. 2013 Nov; 15 (11): 1614. PMCID: PMC3857917

J. Zhang, K. A. Desouza, P. S. Cuculich, D. H. Cooper, J. Chen,  Y. Rudy. Continuous ECGI Mapping of Spontaneous VT Initiation, Continuation and Termination with Antitachycardia Pacing. Heart Rhythm. 2013 Aug;10(8):1244-5. PMCID: PMC3376666

J. Zhang, D.H. Cooper, Y. Rudy. Electrophysiologic mechanism of deteriorating cardiac function in a patient with inappropriate CRT indication and frequent ventricular ectopy. Pacing Clin Electrophysiol. 2013 Aug;36(8):1024-6.PMCID: PMC3729618

D. Jeyaraj, X. Wan, E.Ficker, J.E. Stelzer, I. Deschenes, H. Liu, L. Wilson, K. Decker, T. Said, M. Jain, Y. Rudy, D. Rosenbaum. Ionic bases for electrical remodeling of the  canine cardiac ventricle. Am J Physiol Heart Circ Physiol. August 2013; Volume 305 no. H410-H419DOI: 10.1152/ajpheart.00213.2013. PMCID: PMC3742876

J. Heijman, A. Zaza, D.M. Johnson, Y. Rudy, R.L.M. Peeters, P.G.A. Volders, R.L. Westra. Determinants of Beat-to-Beat Variability of Repolarization Duration in the Canine Ventricular Myocyte: a Computational Analysis. PLoS Computational  Biology. August 2013; Volume 9, Issue 8, e1003202. PMCID: PMC3749940

H.C. Lee, Y. Rudy, P.Y. Chen, S.H. Sheu, J.G. Chang,  J. Cui.  Modulation of KCNQ1 Alternative Splicing Regulates Cardiac IKs Currents and Action Potential Repolarization. Heart Rhythm. 2013 Aug;10(8):1220-1228. PMCID: PMC3771516

Y. Rudy. Noninvasive Electrocardiographic Imaging of Arrhythmogenic Substrates in Humans. Circulation Research. 2013 Mar 1;112(5):863-74. PMCID: PMC3596167

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2012

Livshitz L, Acsai K, Antoons G, Sipido K, Rudy Y.  Data-Based Theoretical Identification of Subcellular Calcium Compartments and Estimation of Calcium Dynamics in Cardiac Myocytes. J Physiol. 2012 Sep 15;590(18):4423-46. doi: 10.1113/jphysiol.2012.228791. Epub 2012 Apr 30. PMCID: PMC3477750

S.B. Marrus, C.M. Andrews, D.H. Cooper, M.N. Faddis, Y. Rudy. Repolarization Changes Underlying Long-Term Cardiac Memory Due to Right Ventricular Pacing: Noninvasive Mapping with ECGI. Circ Arrhythm Electrophysiol. 2012 Aug 1;5(4):773-81. doi: 10.1161/CIRCEP.112.970491. Epub 2012 Jul 6. PMCID: PMC3445629

T. O’Hara, Y. Rudy. Quantitative Comparison of Cardiac Ventricular Myocyte Electrophysiology and Response to Drugs in Human and Non-Human SpeciesAm J Physiol Heart Circ Physiol. 2012 Mar 1;302(5):H1023-30. doi: 10.1152/ajpheart.00785.2011. Epub 2011 Dec 9. PMID: 22159993; PMCID: PMC3311457

T. O’Hara,Y. Rudy. Arrhythmia Formation in Subclinical (“Silent”) Long QT Syndrome Requires Multiple Insults: Quantitative Mechanistic Study Using the KCNQ1 Mutation Q357R as Example. Heart Rhythm. 2012 Feb;9(2):275-82. doi: 10.1016/j.hrthm.2011.09.066. Epub 2011 Sep 25.. PMCID: PMC3443981

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2011

T.A. Quinn et al. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): Standardized reporting for model reproducibility, interoperability, and data sharing. Prog Biophys Mol Biol. 2011 Oct;107(1):4-10. doi: 10.1016/j.pbiomolbio.2011.07.001. PMCID: PMC3190048

P.S. Cuculich, Zhang, J., Y. Wang, K. A. Desouzaa, R. Vijayakumar, P.K. Woodard, Y. Rudy. The Electrophysiologic Cardiac Ventricular Substrate in Patients after Myocardial Infarction: Noninvasive Characterization with ECG Imaging (ECGI). J Am Col Cardiol (JACC). 2011 Oct 25;58(18):1893-902.. PMCID: PMC3365586

A. Nekouzadeh, Y. Rudy. Three Residue Loop Closure in Proteins: A New Kinematic Method Reveals a Locus of Connected Loop Conformations. J Comput Chem. 2011 Sep;32(12):2515-25. doi: 10.1002/jcc.21812. PMCID: PMC4154380

Y. Wang, P.S. Cuculich, J. Zhang, K. A. Desouza, R. Vijayakumar, J. Chen, M. N. Faddis, B. D. Lindsay, T. W. Smith, Y. Rudy. Noninvasive Electroanatomic Mapping of Human Ventricular Arrhythmias Using ECG Imaging (ECGI)Sci Transl Med. 2011 Aug 31;3(98):98ra84. PMCID: PMC3182467

P. Li, Y. Rudy. A Model of Canine Purkinje Cell Electrophysiology and Ca2+ Cycling: Rate Dependence, Triggered Activity and Comparison to Ventricular Myocyte. Circ Res. 2011 Jun 24;109(1):71-9. (Issue Highlight). PMCID: PMC3143030

N. Gaur, Y. Rudy. Multiscale modeling of Ca cycling in cardiac ventricular myocyte: Macroscopic consequences of microscopic dyadic function. Biophys J. 2011 Jun 22;100(12):2904-12. PMCID: PMC3123916

A. Nekouzadeh, Y. Rudy. Continuum Molecular Simulation of Large Conformational Changes during Ion-Channel Gating. PLoS ONE. 2011;6(5):e20186. doi: 10.1371/journal.pone.0020186. Epub 2011 May 20. PMCID: PMC3098872

K. Acsai, G. Antoons, L. Livshitz, Y. Rudy, K. R. Sipido. Microdomain [Ca2+] near ryanodine receptors as reported by L-type Ca2+ and Na/Ca exchange currents. J Phsiol. 2011 May 15;589(Pt 10):2569-83. PMCID: PMC3115826

T.J. O’Hara, L. Virág, A. Varró, Y. Rudy. Simulation of the undiseased human cardiac  ventricular action potential: Model formulation and experimental validationPLoS Comput Biol. 2011 May;7(5):e1002061. PMCID: PMC3102752

S. Ghosh, J.N.A. Silva, R.M. Canham, T.M. Bowman, J. Zhang, E.K. Rhee, P.K. Woodard, Y. Rudy. Electrophysiological Substrate and Intraventricular LV Dyssynchrony in Non-ischemic Heart Failure Patients Undergoing Cardiac Resynchronization Therapy. Heart Rhythm. 2011 May;8(5):692-9. PMCID: PMC3096066

J. Heijman, P.G.A. Volders, R.L. Westra, Y. Rudy. Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient. J Mol Cell Cardiol. 2011 May;50(5):863-71. PMCID: PMC3075371

R.J. van Oort, A. Garbino, W. Wang, S.S. Dixit, A.P. Landstrom, N. Gaur, A.C. De Almeida, D.G. Skapura, Y. Rudy, A.R. Burns, M.J. Ackerman, X.H.T. Wehrens. Disrupted Junctional Membrane Complexes and Hyperactive Ryanodine Receptors Following Acute Junctophilin Knockdown in Mice. Circulation. 2011 Mar 8;123(9):979-88. PMCID: PMC3056402

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2010

K.F. Decker, Y. Rudy. Ionic Mechanisms of Electrophysiological Heterogeneity and Conduction Block in the Infarct Border Zone. Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1588-97. PMCID: PMC2993197

P.S. Cuculich, Y. Wang, B.D. Lindsay, M.N. Faddis, R.B. Schuessler, R.D. Damiano, L. Li, Y. Rudy. Noninvasive Characterization of Epicardial Activation in Humans with Diverse Atrial Fibrillation Patterns. 2010 Oct 5;122(14):1364-72. PMCID: PMC2996091

P.S. Cuculich, Y. Wang, B.D. Lindsay, R. Vijayakumar, Y. Rudy. Noninvasive real-time mapping of an incomplete pulmonary vein isolation using Electrocardiographic Imaging (ECGI). Heart Rhythm. 2010 Sep;7(9):1316-7. PMCID: PMC2888898

J. R. Silva, Y. Rudy. Multi-scale electrophysiology modeling: from atom to organ. J. Gen. Physiol. 2010 Jun;135(6):575-81. PMCID: PMC2888060

D. Wu, K. Delaloye, M. Zaydman, A. Nekouzadeh, Y. Rudy, J. Cui. State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation. J. Gen. Physiol. 2010 Jun;135(6):595-606. PMCID: PMC2888051

N. Varma, P. Jia, C. Ramanathan, Y. Rudy. Right Ventricular Electrical Activation in Heart Failure during Right, Left and Biventricular Pacing. JACC: Cardiovasc. Imaging. 2010 Jun;3(6):567-75. PMCID: PMC2976709

M.P. Latacha, N.B. Memon, P.S. Cuculich, J. Hertel, Y. Wang, Y. Rudy, T.W. Smith. Pathologic Examination after Epicardial Ablation of VT in Cardiac Sarcoidosis. Heart Rhythm. 2010 May;7(5):705-7. PMCID: PMC4140187

S. Ghosh, D.H. Cooper, R. Vijayakumar, J. Zhang, S. Pollak, M. Haissaguerre, Y. Rudy. Early repolarization associated with sudden death: Insights from noninvasive Electrocardiographic Imaging (ECGI). Heart Rhythm. 2010 Apr;7(4):534-7. PMCID: PMC2865425

Y. Rudy. Noninvasive imaging of cardiac electrophysiology and arrhythmia. Annals N.Y. Academy of Sciences. 2010 Feb;1188:214-21. PMID: 20201906

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2009

N. Gaur, Y. Rudy, L. Hool. Contributions of ion-channel currents to ventricular action potential changes and induction of early afterdepolarizations during acute hypoxia. Circ Res. 2009 Dec 4;105(12):1196-203. doi: 10.1161/CIRCRESAHA.109.202267. Epub 2009 Oct 29. PMCID: PMC2826175

Y. Rudy. Cardiac repolarization: Insights from mathematical modeling and electrocardiographic imaging (ECGI). Heart Rhythm. 2009 Nov;6(11 Suppl):S49-55. doi: 10.1016/j.hrthm.2009.07.021. Epub 2009 Sep 1. PMID: 19880074

L. Livshitz, Y. Rudy. Uniqueness and Stability of Action Potential Models during Rest, Pacing, and Conduction Using Problem-Solving Environment. Biophys J. 2009 Sep 2;97(5):1265-76. doi: 10.1016/j.bpj.2009.05.062. PMCID: PMC2749757

J.N. Silva, S. Ghosh, T. M. Bowman, E. K. Rhee, P. M. Woodard, Y. Rudy, Cardiac Resynchronization Therapy in Pediatric Congenital heart Disease: Insights from Noninvasive Electrocardiographic Imaging. Heart Rhythm. 2009 Aug;6(8):1178-85. doi: 10.1016/j.hrthm.2009.04.017. Epub 2009 Apr 15. PMCID: PMC2717033

J.R. Silva, H. Pan, D. Wu, A. Nekouzadeh, K. Decker, J. Cui, N. A. Baker, D. Sept, Y. Rudy. A Multiscale Model Linking Ion-Channel Molecular Dynamics and Electrostatics to the Cardiac Action Potential. Proc Natl Acad Sci USA (PNAS). 2009 Jul 7;106(27):11102-6. PMCID: PMC2700153

S. Ghosh, Y. Rudy. Application of L1-Norm Regularization to Epicardial Potential Solution of the Inverse Electrocardiography Problem. Ann Biomed Eng. 2009 May;37(5):902-12. doi: 10.1007/s10439-009-9665-6. Epub 2009 Mar 6. PMCID: PMC2958169

K. F. Decker, J. Heijman, J.R. Silva, T. J. Hund, Y. Rudy. Properties and Ionic Mechanisms of Action Potential Adaptation, Restitution and Accommodation in Canine Epicardium. Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1017-26. doi: 10.1152/ajpheart.01216.2008. Epub 2009 Jan 23. PMCID: PMC2670702

Y. Wang and Y. Rudy. Electrocardiographic Imaging (ECGI) of Normal Human Atrial Repolarization. Heart Rhythm. 2009 Apr;6(4):582-3. doi: 10.1016/j.hrthm.2008.07.024. Epub 2008 Jul 31. PMCID: PMC276717

M. Haissaguerre, JJ Schott, F Sacher, G Lousouran, R Weerasooriya, V Probst, M Horlitz,R Liersch, S LeScouarnec, M Hocini, P Bordachar, P Jais, A Wilde, C Nichols, Y Rudy, H LeMarec. Ventricular fibrillation with prominent early repolarization changes associated to KCNJ8/KATP channel mutation. J Cardiovasc Electrophysiol. 2009 Jan;20(1):93-8. doi: 10.1111/j.1540-8167.2008.01326.x. PMID: 19120683

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2008

S. Ghosh, J.N. Avari, E.K. Rhee, P.K. Woodard, Y. Rudy. Hypertrophic Cardiomyopathy with Pre-excitation: Insights from Noninvasive Electrocardiographic Imaging (ECGI) and Catheter Mapping. J Cardiovasc Electrophysiol. 2008 Nov;19(11):1215-7. doi: 10.1111/j.1540-8167.2008.01203.x. Epub 2008 May 9. PMCID: PMC2631093

A. Nekouzadeh, J. Silva, Y. Rudy. Modeling subunit cooperativity in opening of tetrameric ion channels. Biophys J. 2008 Oct;95(7):3510-20. doi: 10.1529/biophysj.108.136721. Epub 2008 Jul 11. PMCID: PMC2547442

H Sale, J Yang, TJ O’Hara, DJ Tester, P Phartiyal, JQ He, Y Rudy, MJ Ackerman, GA Robertson. Physiological properties of hERG 1a/1b heteromeric currents and hERG 1b-specific mutation associated with long-QT syndrome. Circ Res. 2008 Sep 26;103(7):e81-95. doi: 10.1161/CIRCRESAHA.108.185249. Epub 2008 Sep 5. PMCID: PMC2761010

Y. Rudy, M.J. Ackerman, D. M. Bers, C. E. Clancy, S. R. Houser, B. London, A. D. McCulloch, D. A. Przywara, R. L. Rasmusson, R. J. Solaro, N. A. Trayanova, D. R. Van Wagoner, A. Varró, J. N. Weiss, D. A. Lathrop. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 2008 Sep 9;118(11):1202-11. doi: 10.1161/CIRCULATIONAHA.108.772715. PMCID: PMC2908516

T.J. Hund, K.F. Decker, E. Kanter, P.J. Mohler, P.A. Boyden, R.B. Schuessler, K.A. Yamada, Y. Rudy. Role of activated CaMKII in abnormal calcium homeostasis and INa remodeling after myocardial infarction: Insights from mathematical modeling. J Mol Cell Cardiol. 2008 Sep;45(3):420-8. doi: 10.1016/j.yjmcc.2008.06.007. Epub 2008 Jun 28. PMCID: PMC2587155

S. Ghosh, E.K. Rhee, J.N. Avari, P.K. Woodard, Y. Rudy. Cardiac Memory in Wolff-Parkinson-White Patients: Noninvasive Imaging of Activation and Repolarization before and after Catheter Ablation. Circulation. 2008 Aug 26;118(9):907-15. doi: 10.1161/CIRCULATIONAHA.108.781658. Epub 2008 Aug 12. PMCID: PMC2747627

N. Varma, P. Jia, Y. Rudy. Placebo CRT. J Cardiovasc Electrophysiol. 2008 Aug;19(8):878. doi:10.1111/j.1540-8167.2007.01075.x. Epub 2008 Feb 13. PMCID: PMC2957367

M. Bebarova, T. O’Hara, J.L.M.C. Geelen, R.J. Jongbloed, C. Timmermans, Y.H. Arens, L.M. Rodriguez, Y. Rudy, P.G. Volders. Subepicardial phase-0 block and discontinuous transmural conduction underlie right-precordial ST-segment elevation by a SCN5A loss-of-function mutation. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H48-58. PMCID: PMC2494753

S. Ghosh, J.N. Avari, E.K. Rhee, P.K. Woodard, Y. Rudy. Noninvasive Electrocardiographic Imaging (ECGI) of Epicardial Activation before and after Ablation of Accessory Pathway in a Patient with Ebstein’s Anomaly. Heart Rhythm. 2008 Jun;5(6):857-60. doi: 10.1016/j.hrthm.2008.03.011. Epub 2008 Mar 14. PMCID: PMC2967218

S. Ghosh, J.N. Avari, E.K. Rhee, P.K. Woodard, Y. Rudy. Noninvasive Electrocardiographic Imaging (ECGI) of a Univentricular Heart with Wolff-Parkinson-White Syndrome. Heart Rhythm. Apr;5(4):605-8. doi: 10.1016/j.hrthm.2007.12.018. Epub 2008 Feb 4. PMCID: PMC2329801

Y. Wang, Li Li, P.S. Cuculich, Y. Rudy. Electrocardiographic Imaging of Ventricular Bigeminy in a Human Subject. Circ Arrhythm Electrophysiol. 2008 Apr;1(1):74-5. doi: 10.1161/CIRCEP.107.753194. PMCID: PMC2586178

Y. Rudy. Molecular Basis of Cardiac Action Potential Repolarization. Ann N Y Acad Sci. 2008 Mar;1123:113-8. doi: 10.1196/annals.1420.013. PMID: 18375583

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2007

Y. Wang, R.B.Schuessler, R.J.Damiano, P.K. Woodard, Y. Rudy. Noninvasive Electrocardiographic Imaging (ECGI) of Scar-Related Atypical Atrial Flutter. Heart Rhythm. 2007 Dec;4(12):1565-7. Epub 2007 Aug 29. PMCID: PMC2189983

A. Nekouzadeh, Y. Rudy. Statistical Properties of Ion Channel records: II. Estimation from the Macroscopic Current. Math Biosci. 2007 Nov;210(1):315-34. Epub 2007 May 4. PMCID: PMC2151058

A. Nekouzadeh, Y. Rudy. Statistical Properties of Ion Channel records: I. Relationship to the Macroscopic Current. Math Biosci. 2007 Nov;210(1):291-314. Epub 2007 May 4. PMCID: PMC2121577

Y. Rudy. Modeling the Molecular Basis of Cardiac Repolarization. Europace. 2007 Nov;9 Suppl 6:vi17-9. PMID: 17959688

C. Clancy, Z.I. Zhu, Y. Rudy. Pharmacogenetics and Anti-arrhythmic Drug Therapy: A Theoretical Investigation. Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H66-75. Epub 2006 Sep 22.PMCID: PMC2034498

Y. Wang, P.S. Cuculich, P.K. Woodard, B.D. Lindsay, Y. Rudy. Focal Atrial Tachycardia after Pulmonary Vein Isolation: Noninvasive Mapping with Electrocardiographic Imaging (ECGI). Heart Rhythm. 2007 Aug;4(8):1081-4. Epub 2007 May 4. PMCID: PMC2078529

G. Faber, Y. Rudy. Calsequestrin Mutation and Catecholaminergic Polymorphic Ventricular Tachycardia: A Simulation Study of Cellular Mechanism. Cardiovasc Res. 2007 Jul 1;75(1):79-88. Epub 2007 Apr 21. PMCID: PMC2030636

L. Livshitz, Y. Rudy. Regulation of Ca2+ and Electrical Alternans in Cardiac Myocytes: Role of CaMKII and Repolarizing Currents. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2854-66. Epub 2007 Feb 2. PMCID: PMC2274911

G.M. Faber, J. Silva, L. Livshitz, Y. Rudy. Kinetic Properties of the Cardiac L-type Ca2+ Channel and its Role in Myocyte Electrophysiology: A Theoretical Investigation. Biophys J. 2007 Mar 1;92(5):1522-43. Epub 2006 Dec 8. PMCID: PMC1796810

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2006

Y. Rudy. Noninvasive Electrocardiographic Imaging of Cardiac Resynchronization Therapy in Patients with Heart Failure. J Electrocardiol. 2006 Oct;39(4 Suppl):S28-30. Epub 2006 Sep 6. PMCID: PMC1959340

Y. Wang, Y. Rudy. Application of the Method of Fundamental Solutions to Potential-based Inverse Electrocardiography. Ann Biomed Eng. 2006 Aug;34(8):1272-88. Epub 2006 Jun 29. PMCID: PMC2440514

C. Ramanathan, P. Jia, R.N. Ghanem, K. Ryu, Y. Rudy. Activation and repolarization of the normal human heart under complete physiological condition. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6309-14. Epub 2006 Apr 10. PMCID: PMC1458874

P. Jia, C. Ramanathan, R.N. Ghanem, K. Ryu, N. Varma, Y. Rudy. Electrocardiographic Imaging of Cardiac Resynchronization Therapy in Heart Failure: Observations of Variable Electrophysiological Responses. Heart Rhythm. 2006 Mar;3(3):296-310.PMCID: PMC2030622

Y. Rudy, J.R. Silva. Computational Biology in the Study of Cardiac Ion Channels and Cell Electrophysiology. Q Rev Biophys. 2006 Feb; 39(1): 57–116. PMCID: PMC1994938

Y. Rudy. Modeling and Imaging Cardiac Repolarization Abnormalities. J Intern Med. 2006 Jan;259(1): 91–106. PMCID: PMC1865512

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2005

A. Intini, R.N. Goldstein, P. Jia, C. Ramanathan, K. Ryu, B. Giannattasio, R. Gilkeson, B.S. Stambler, P. Brugada, W.G. Stevenson, Y. Rudy, A.L. Waldo. Electrocardiographic Imaging (ECGI), a Novel Diagnostic Modality used for Mapping of Focal Left Ventricular Tachycardia in a Young Athlete. Heart Rhythm Journal. 2005 Nov;2:1250-1252. PMCID: PMC2000800

Y. Rudy. Noninvasive Electrocardiographic Imaging in Humans J Electrocardiol . 2005 Oct;38:138-140. PMID: 16226089

Y. Rudy. Lessons Learned about Slow Discontinuous Conduction from Models of Impulse Propagation. J Electrocardiol. 2005 Oct;38:52-54. PMID: 16226074

J. Silva, Y. Rudy. Subunit Interaction Determines IKs Participation in Cardiac Repolarization and Repolarization reserve. Circulation. 2005 Sep;112:1384-1391. PMCID: PMC1820744

S. Ghosh, Y. Rudy. Accuracy of Quadratic versus Linear Interpolation in Noninvasive Electrocardiographic Imaging (ECGI). Annals of Biomed Eng. 2005 Sep;33:1187-1201. PMCID: PMC2151917

R.N. Ghanem, P. Jia, C. Ramanathan, K. Ryu, A. Markowitz, Y. Rudy. Noninvasive Electrocardiographic Imaging (ECGI): Comparison to Intraoperative Mapping in Patients. Heart Rhythm Journal. 2005 Apr;2:339-354. PMCID: PMC1949041

L. Livshitz, K. Decker, G. Faber, T. O’Hara, J. Silva, Y. Rudy. Comments on a Model for Human Ventricular Tissue. Am J Physiol Heart Circ Physiol. 2005 Jan;288:H453- H454 (letter). PMID: 15598875

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2004

T. O’Hara, K. Decker, G. Faber, L. Livshitz, J. Silva, Y. Rudy. Comments on: Role of Individual Ionic Current Systems in Ventricular Cells Hypothesized by Model Study. Jpn J Physiol. 2004 Oct;54:505-508 (letter). PMID: 15667675

T.J. Hund, Y. Rudy. Rate Dependence and Regulation of Action Potential and Calcium Transient in a Canine Cardiac Ventricular Cell Model. Circulation. 2004 Oct;110:3168-3174. PMCID: PMC1851913

Y. Rudy. From Genetics to Cellular Function Using Computational Biology. Annals N.Y. Academy of Science. 2004 May;1015:261-270. PMID: 15201166

Y. Rudy. Genetic Defects, Ionic Currents and Electrocardiographic Alterations. Annals of Medicine. 2004;36:15-21. PMID: 15176419

C. Ramanathan, R.N. Ghanem, P. Jia, K. Ryu, Y. Rudy. Electrocardiographic Imaging (ECGI): A Noninvasive Imaging Modality for Cardiac Electrophysiology and Arrhythmia. Nature Medicine. 2004 Apr;10:422-428. PMCID: PMC1950745

A.G. Kleber, Y. Rudy. Basic Mechanisms of Cardiac Impulse Propagation and Reentrant Arrhythmias. Physiological Reviews. 2004 Apr;84:431-488. PMID: 15044680

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2003

R.N. Ghanem, C. Ramanathan, P. Jia, Y. Rudy. Heart-Surface Reconstruction and ECG Electrodes Localization Using Fluoroscopy, Epipolar Geometry and Stereovision: Application to noninvasive imaging of cardiac electrical activity. IEEE Trans on Medical Imaging. 2003 Oct;22:1307-1318. PMCID: PMC2034496

C. Ramanathan, P. Jia, R.N. Ghanem, D. Calvetti, Y. Rudy. Noninvasive Electrocardiographic Imaging (ECGI): Application of the Generalized Minimal Residual (GMRes) Method. Annals of Biomedical Engineering. 2003 Sep;31:981-994. PMCID: PMC2151914

S.P. Thomas, J.P. Kucera, L. Bircher-Lehman, Y. Rudy , J.E. Saffitz, A.G. Kleber. Impulse Propagation in Synthetic Strands of Neonatal Cardiac Myocytes with Genetically Reduced Levels of Connexin43. Circulation Research. 2003 May;92:1209-1216. PMCID: PMC2242733

J. Silva, Y. Rudy. Pacemaking Activity in Ventricular Myocytes Under Downregulation of Ik1: A Study of Mechanism. Circulation Research. 2003 Jan;92:261-263. PMCID: PMC1890031

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2002

J.P. Kucera, S. Rohr, Y. Rudy. Localization of Sodium Channels in Intercalated Discs Modulates Cardiac Conduction. Circulation Research. 2002 Nov;91:1176-1182. PMCID: PMC1888562

P. Jia, B.Punske, B.Taccardi, Y. Rudy. Endocardial Mapping of Electrophysiologically Abnormal Substrates and Cardiac Arrhythmias using a Noncontact Nonexpandable Catheter. J Cardiovasc Electrophysiol . 2002 Sep;13:888-895. PMCID: PMC2034341

C.E. Clancy, Y. Rudy. A Na+ Channel Mutation that Causes Both Brugada and Long QT Syndrome Phenotypes: A Simulation Study of Mechanism. Circulation. 2002 Mar 12;105:1208-1213. PMCID: PMC199727

K. Gima, Y. Rudy. Ionic Current Basis of Electrocardiographic Waveforms: A Model Study. Circulation Research. 2002 Mar;90:889-896. PMCID: PMC1847799

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2001

T.J. Hund, J.P. Kucera, N.F. Otani, Y. Rudy. Ionic Charge Conservation and Long – Term Steady State in the Luo-Rudy Dynamic Cell Model. Biophys J. 2001 Dec;81:3324-3331. PMCID: PMC1301789

J. E. Burnes, B. Taccardi, P. Ershler, Y. Rudy. Noninvasive ECG Imaging of Substrate and Intramural Ventricular Tachycardia in Infarcted Hearts. J Amer College Cardiol(JACC) 2001 Dec;38:2071-2078. PMCID: PMC2223074

Y. Rudy, together with other 23 members of the Sicilian Gambit on Cardiac Arrhythmia, “New Approaches to Antiarrhythmic Therapy: Emerging Therapeutic Applications of the Cell Biology of Cardiac Arrhythmias”, Part II. Circulation 2001 Dec;104:2990-2994. Co-Published in European Heart Journal, and Cardiovascular Research. PMID: 11739317

Y. Rudy, together with other 23 members of the Sicilian Gambit on Cardiac Arrhythmia. New Approaches to Antiarrhythmic Therapy: Emerging Therapeutic Applications of the Cell Biology of Cardiac Arrhythmias”, Part I. Circulation 2001 Dec;104:2865-2873. Co-Published in European Heart Journal, and Cardiovascular Research. PMID: 11733408

J.P. Kucera, Y. Rudy. Mechanistic Insights into Very Slow Conduction in Branching Cardiac Tissue: A Model Study. Circ Res 2001 Oct;89:799-806. PMID: 11679410

Y. Rudy. The Ionic Mechanisms of Conduction in Cardiac Tissue. J Electrocardiology. 2001 Oct;34:65-68. PMID: 11781938

D. Nuyens, M. Stengl, S. Dugarmaa, T. Rossenbacker, V. Compernolle, Y. Rudy, J.F. Smits, W. Flameng, C.E. Clancy, L. Moons, M.A. Vos, M. Dewerchin, K. Benndorf, D. Collen, E. Carmeliet, P. Carmeliet. Abrupt Rate Accelerations or Premature Beats Cause Life Threatening Arrhythmias in Mice with Long-QT3 Syndrome. Nature Medicine. 2001 Sep; 7:1021-1027. PMID: 11533705

R.N. Ghanem, J.E. Burnes A.L. Waldo, Y. Rudy. Imaging Dispersion of Myocardial Repolarization II. Noninvasive Reconstruction of Epicardial Measures. Circulation. 2001 Sep;104:1306-1312. PMID: 11551884

J.E. Burnes, R.N. Ghanem, A.L. Waldo, Y. Rudy. Imaging Dispersion of Myocardial Repolarization I. Comparison of Body Surface and Epicardial Measures. Circulation. 2001 Sep;104:1299-1305. PMID: 11551883

D. Noble, Y. Rudy. Models of Cardiac Ventricular Action Potentials: Iterative Interaction Between Experiment and Simulation. Philosophical Transactions Royal Society (London). 2001 Jun;359:1127-1142.

C. E. Clancy, Y. Rudy. Cellular Consequences of HERG Mutations in the Long QT Syndrome: Precursors to Sudden Cardiac Death. Cardiovascular Research. 2001 May;50:301-313. PMID: 11334834

C. Ramanathan, Y. Rudy. Electrocardiographic Imaging:II. Effect of Torso Inhomogeneities on the Noninvasive Reconstruction of Epicardial Potentials, Electrograms and Isochrones. J Cardiovasc Electrophysiol. 2001 Feb; 12:241-252. PMID: 11232625

C. Ramanathan, Y. Rudy. Electrocardiographic Imaging: I. Effect of Torso Inhomogeneities on Body Surface Electrocardiographic Potentials. J Cardiovasc Electrophysiol. 2001 Feb;12:229-240. PMID: 11232624

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2000

J.E. Burnes, B. Taccardi, R.S. MacLeod, Y. Rudy. Noninvasive Electrocardiographic Imaging of Electrophysiologically Abnormal Substrate in Infarcted Hearts: A Model Study. Circulation. 2000 Feb;101:533-540. PMID: 10662751

P.C. Viswanathan, Y. Rudy. Cellular Arrhythmogenic Effects of the Congenital and Acquired Long QT Syndrome in the Heterogeneous Myocardium. Circulation. 2000 Mar;101:1192-1198. PMID: 10715268

Y. Wang, Y. Rudy. Action Potential Propagation in Inhomogeneous Cardiac Tissue: Safety Factor Considerations and Ionic Mechanism. Am J Physiol (Heart). 2000 Apr;278:H1019- H1029. PMID: 10749693

G.M. Faber, Y. Rudy. Action Potential and Contractility Changes in [Na+]i Overloaded Cardiac Myocytes: A Simulation Study. Biophys J . 2000 May; 78:2392-2404. PMCID: PMC1300828

Y. Rudy. From Genome to Physiome: Integrative Models of Cardiac Excitation. Annals of Biomedical Engineering. 2000 Aug;28:945-950. PMID: 11144679

J.E. Burnes, B. Taccardi, Y. Rudy. A Noninvasive Imaging Modality for Cardiac Arrhythmias. Circulation. 2000 Oct;102:2152-2158. PMCID: PMC2034298

T.J. Hund, N.F. Otani, Y. Rudy. The Dynamics of Action Potential Head-Tail Interaction During Reentry in Cardiac Tissue: Ionic Mechanisms. Am J Physiol (Heart). 2000 Oct;279:H1869-H1879. PMID: 11009475

E. Ficker, D. Thomas, P.C. Viswanathan, A. T. Dennis, S. G. Priori, C. Napolitano, M. Memmi, B.A. Wible, E. S. Kaufman, S. Iyengar, P. J. Schwartz, Y. Rudy, A.M. Brown. Novel Characteristics of a Misprocessed Mutant HERG Channel Linked to Hereditary Long QT Syndrome. Am J Physiol (Heart). 2000 Oct;279:H1748-H1756. PMID: 11009462

P. Jia, B. Punske, B. Taccardi, Y. Rudy. Electrophysiologic Endocardial Mapping from a Noncontact Nonexpandable Catheter: A Validation Study of a Geometry-Based Concept. J Cardiovasc Electrophysiol. 2000 Nov;11:1238-1251. PMID: 11083245

T.J. Hund, Y. Rudy. Determinants of Excitability in Cardiac Myocytes: Mechanistic Investigation of Memory Effect. Biophys J. 2000 Dec;79:3095-3104. PMCID: PMC1301186

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1999

Y. Rudy, J.E. Burnes. Noninvasive Electrocardiographic Imaging. Annals of Noninvasive electrocardiology. 1999 Oct;4:340-359. doi: 10.1111/j.1542-474X.1999.tb00220.x

C. E. Clancy, Y. Rudy. Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia. Nature. 1999 Aug;400:566-569. PMID: 10448858

Y.H. He, R.N. Ghanem, A.L. Waldo, Y. Rudy. An Interactive Graphical System for Automated Mapping and Display of Cardiac Rhythms. J Electrocardiology. 1999 Jul;32:225-241. PMID: 10465566

P.C. Viswanathan, R.M. Shaw, Y. Rudy. Effects of Ikr and Iks Heterogeneity on Action Potential Duration and its Rate-Dependence: A Simulation Study. Circulation. 1999 May;99:2466-2474. PMID: 10318671

P.C. Viswanathan, Y. Rudy. Pause Induced Early Afterdepolarizations in the Long QT Syndrome: A Simulation Study. Cardiovascular Research. 1999 May;42:530-542. PMID: 10533588

Y. Rudy. ECGI: A Noninvasive Imaging Modality for Characterization of Intramural Myocardial Activation. J Electrocardiology. 1999 Apr;32: 1-6. PMID: 10688295

S.G. Priori, J. Barhanin, R.N.W. Hauer, W. Haverkamp, H.J. Jongsma, A.G. Kleber, W.J. McKenna, D.M. Roden, Y. Rudy, K. Schwartz, P.J. Schwartz, J.A. Towbin, A.M. Wilde. Genetic and Molecular Basis of Cardiac Arrhythmias, Parts I and II. Circulation. 1999 Feb;99:518-528. Also published in Eur Heart J. (1999) 20, 174-195. PMID: 9927398

S.G. Priori, J. Barhanin, R.N.W. Hauer, W. Haverkamp, H.J. Jongsma, A.G. Kleber, W.J. McKenna, D.M. Roden, Y. Rudy, K. Schwartz, P.J. Schwartz, J.A. Towbin, A.M. Wilde. Genetic and Molecular Basis of Cardiac Arrhythmias, Part III. Circulation. 1999 Feb;99:674-681. Also published in Eur Heart J. (1999) 20, 174-195. PMID: 9950666

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1998

Z.W. Liu, P.Jia, L.A. Biblo, B. Taccardi, Y. Rudy. Single-Beat Endocardial Mapping from a Noncontact Nonexpandable 9F Catheter: A Feasibility Study. Annals of Biomedical Engineering. 1998 Nov-Dec;26:994-1009. PMID: 9846938

H.S. Oster, B. Taccardi, R.L. Lux, P.R. Ershler, Y. Rudy. Electrocardiographic Imaging: Noninvasive Characterization of Intramural Myocardial Activation from Inverse Reconstructed Epicardial Potentials and Electrograms. Circulation 1998 Apr;97:1496-1507. PMID: 9214798

J.E. Burnes, D.C. Kaelber, B. Taccardi, R.L. Lux, P.R. Ershler, Y. Rudy. A Field-Compatible Method for Interpolating Biopotentials: Development and Evaluation in Electrocardiographic Imaging. Annals of Biomedical Engineering 1998 Jan-Feb;26:37-47. PMID: 10355549

Y. Rudy, B. Taccardi. Noninvasive Imaging and Catheter Imaging of Potentials, Electrograms and Isochrones on the Ventricular Surfaces. J Electrocardiology. 1998;30 Suppl:19-23. PMID: 9535475

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1997

R.M. Shaw and Y. Rudy. Ionic Mechanisms of Propagation in Cardiac Tissue: Roles of the Sodium and L-Type Calcium Currents During Reduced Excitability and Decreased Gap-Junction Coupling. Circ Res. 1997 Nov;81:727-741. PMID: 9351447

K.R. Laurita, S.D. Girouard, Y. Rudy, D.S. Rosenbaum. Role of Passive Electrical Properties During Action Potential Restitution in the Intact Heart. Am J. Physiol. 1997 Sep;273:H1205-H1214. PMID: 9321808

H.S.Oster, B.Taccardi, R.L. Lux, P.R. Ershler, Y. Rudy. Noninvasive Electrocardiographic Imaging: Reconstruction of Epicardial Potentials, Electrograms and Isochrones, and Localization of Single and Multiple Electrocardiac Events. Circulation. 1997 Aug;96:1012-1024. PMID:9264513

R.M. Shaw and Y. Rudy. Electrophysiologic Effects of Acute Myocardial Ischemia: A Theoretical Study of Altered Cell Excitability and Action Potential Duration. Cardiovascular Research. 1997 Aug;35:256-272. PMID: 9349389

Z.W. Liu, P.Jia, P.R.Ershler, B.Taccardi, R.L. Lux, D.S. Khoury, Y. Rudy. Noncontact Endocardial Mapping: Reconstruction of Electrograms and Isochrones from Intracavitary Probe Potentials. J Cardiovasc Electrophys. 1997 Apr;8:415-431. PMID: 9106427

H.S. Oster and Y. Rudy. Regional Regularization of the Electrocardiographic Inverse Problem: A Model Study using Spherical Geometry. IEEE Trans BME. 1997 Feb;44: 188-199. PMID: 9214798

Y. Rudy, and R.M. Shaw. Cardiac Excitation: An Interactive Process of Ion Channels and Gap Junctions. Adv Exp Med Biol. 1997; 430: 269-280. PMID: 9330736

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1995

J. Zeng, K. R. Laurita, D. S. Rosenbaum, and Y. Rudy. Two Components of the Delayed Rectifier K+ Current in Ventricular Myocytes of the Guinea Pig Type: Theoretical Formulation and their Role in Repolarization. Circulation Research. 1995 Jul;77:1-13. PMID: 7788872

Y. Rudy. Reentry: Insights from Theoretical Simulations in a Fixed Pathway. J Cardiovascular Electrophysiology. 1995 Apr;6:294-312. PMID: 7544193

Y. Rudy. Model Studies of Cellular Excitation. Adv Exp Med Biol. 1995; 382: 67-77. PMID: 8540415

J. Zeng and Y. Rudy. Early Afterdepolarizations in Cardiac Myocytes: Mechanism and Rate Dependence. Biophys J. 1995 Mar;68:949-964. PMCID: PMC1281819

R.M. Shaw and Y. Rudy. The Vulnerable Window for Unidirectional Block in Cardiac Tissue: Characterization and Dependence on Membrane Excitability and Cellular Coupling. J Cardiovascular Electrophysiology. 1995 Feb;6:115-131. PMID: 7780627

D.S. Khoury, B. Taccardi, R.L. Lux, P.R. Ershler, and Y. Rudy. Reconstruction of Endocardial Potentials and Activation Sequences from Intracavitary Probe Measurements: Localization of Pacing Sites and Effects of Myocardial Structure. Circulation 1995 Feb;91:845-863. PMID: 7828314

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1994

S. Niwano, J.Ortiz, H. Abe, X. Gonzalez, Y. Rudy, and A.L. Waldo. Characterization of the excitable gap in a functionally determined reentrant circuit. Circulation. 1994 Oct;90:1997-2014. PMID: 7522990

D.W. Whalley, D.J. Wendt, C.F. Starmer, Y. Rudy, and A.O. Grant. Voltage- Independent Effects of Extracellular K+ on the Na+ Current and Phase 0 of the Action Potential in Isolated Cardiac Myocytes. Circulation Research 1994 Sep;75:491-502. PMID: 8062422

C. Luo and Y. Rudy. A Dynamic Model of the Cardiac Ventricular Action Potential: II. Afterdepolarizations, Triggered Activity and Potentiation. Circulation Research. 1994 Jun;74:1097-1113. PMID:7514510

C. Luo and Y. Rudy. A Dynamic Model of the Cardiac Ventricular Action Potential: I. Simulations of Ionic Currents and Concentration Changes. Circulation Research. 1994 Jun;74:1071-1096. PMID:7514509

J. Ortiz, A. Nozaki, A. Shimizu, Y. Rudy, and A.Waldo. Mechanism of Interruption of Atrial Flutter by Moricizine: Electrophysiological and Multiplexing Studies in the Canine Sterile Pericarditis Model of Atrial Flutter. Circulation. 1994 Jun;89(6):2860-9. PMID: 8205702

J. Ortiz, S. Niwano, H. Abe, H.X. Gonzalez, Y. Rudy, N. Johnson and A.L. Waldo. Mapping the Conversion of Atrial Flutter to Atrial Fibrillation and Atrial Fibrillation to Atrial Flutter – Insights into Mechanism. Circulation Research. 1994 May;74(5):882-94. PMID:8156635

F. Dexter, Y. Rudy, and G.M. Saidel. Mathematical Model of Acetylcholine Kinetics in Neuroeffector Junctions. Am J Physiol. 1994 Jan;266(1 Pt 2):H298-309. PMID: 8304512

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1992

D. Khoury and Y. Rudy. A Model Study of Volume Conductor Effects on Endocardial and Intracavitary Potentials. Circulation Research. 1992 Sep;71:511-525. PMID: 1499104

H.S. Oster and Y. Rudy. The Use of Temporal Information in the Regularization of the Inverse Problem of Electrocardiography. IEEE Trans Biomed Eng. 1992 Jan;39:65-75. PMID: 1572683

Y. Rudy and H.S. Oster. The Electrocardiographic Inverse Problem. CRC Critical Reviews in Biomedical Engineering 1992;20:25-46. PMID:1424685

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1991

W. Quan and Y. Rudy. Termination of Reentrant Propagation by a Single Stimulus – A Model Study. PACE. 1991 Nov;14:1700-1706. PMID:1721161

Y. Rudy and W. Quan. Propagation Delays Across Gap Junctions and their Reflection in Extracellular Potentials: a Simulation Study. J Cardiovascular Electrophysiology. 1991 Aug;2:299-315.

C. Luo and Y. Rudy. A Model of the Ventricular Cardiac Action Potential: Depolarization, Repolarization and their Interaction. Circulation Research. 1991 Jun;68:1501-1526. PMID: 1709839

F. Dexter, Y. Rudy, M.N. Levy, and E.N. Bruce. Mathematical Model of Cellular Basis for the Respiratory Sinus Arrhythmia. J Theor Biol. 1991 May;150:157-173. PMID: 1890853

A. Shimizu, A. Nozaki, Y. Rudyand A.L. Waldo. Onset of Induced Atrial Flutter in the Canine Pericarditis Model. J Amer College Cardiol. 1991 Apr;17: 1223-1234. PMID: 2007723

J. Liebman, B. Olshansky, A. Zeno, A. Geha, Y. Rudy, W. Henthorn, M. Cohen, and A.L. Waldo. Electrocardiographic Body Surface Potential Mapping in the Wolff – Parkinson -White Syndrome: Non-invasive Determination of the Ventricular Insertion Sites of AV Connections. Circulation. 1991 Mar;83:886-901. PMID: 1999038

A. Shimizu, A. Nozaki, Y. Rudy and A.L. Waldo. Multiplexing Studies of the Effects of Rapid Atrial Pacing on the Area of Slow Conduction During Atrial Flutter in the Canine Pericarditis Model. Circulation. 1991 Mar;83:983-994. PMID: 1999046

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1990

Y. Reich, C.W. Thomas, J. Liebman, Y.H. Pao, and Y. Rudy. Multi-Category Classification of Body Surface Potential Maps. IEEE Trans Biomed Eng BME. 1990 Oct;37:945-955. PMID: 2249867

B.J. Messinger-Rapport and Y. Rudy. Non-Invasive Recovery of Epicardial Potentials in a Realistic Heart-Torso Geometry: Normal Sinus Rhythm. Circulation Research. 1990 Apr;66:1023-1039. PMID: 2317885

W. Quan and Y. Rudy. Unidirectional Block and Reentry of Cardiac Excitation-A Model Study. Circulation Research. 1990 Feb;66:367-382. PMID: 2297808

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1989

D. Khoury, H. McAlister, B. Wilkoff, T. Simmons, Y. Rudy, R. McCowan, V. Morant, L. Castle, and J. Maloney. Continuous Right Ventricular Volume Assessment by Catheter Measurement of Impedance for Antitachycardia System Control. PACE. 1989 Dec;12(12):1918-26. PMID: 2481290

F. Dexter, G.M. Saidel, and Y. Rudy. Simulation of the diffusion of Acetylcholine in the Neuroeffector Junctions of the Sinus Node. J Theo Boils. 1989 Dec 19;141(4):505-14. PMID: 2630802

F. Dexter, M.N. Levy, Y. Rudy. Mathematical Model of the Changes in Heart Rate Elicited by Vagal Stimulation. Circulation Research. 1989 Nov;65:1330-1339. PMID: 2805246

B.J. Messinger-Rapport and Y. Rudy. Computational Issues of Importance to the Inverse Recovery of Epicardial Potential in a Realistic Heart-Torso Geometry. Mathematical Biosciences. 1989 Nov;97(1):85-120.

J. Liebman, C.W. Thomas, R. Fraenkel, and Y. Rudy. Analysis of the Hypoplastic Right Ventricle Utilizing Electrocardiographic Body Surface Potential Mapping. J Electrocardiology. 1989 Jul;22(3):195-209. PMID: 2760554

F. Dexter, Y. Rudy, M.N. Levy. Muscarinic Autoreceptors do not Modulate Kinetics of Acetylcholine Release in Hearts. Am J Physiol. 1989 Apr;256(4 Pt 2):H1073-8. PMID: 2705550

F. Dexter, G.M. Saidel, M.N. Levy, and Y. Rudy. Mathematical Model of the Dependence of Heart Rate on the Tissue Concentration of Acetylcholine. Am J Physiol. 1989 Feb;256(2 Pt 2):H520-6. PMID: 2916685

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1988

J.N. Amoore, Y. Rudy, and J. Liebman. Respiration and the ECG. A Study Using Body Surface Potential Maps. J Electrocardiology. 1988 Aug;21(3):263-71. PMID: 3171459

B.J. Messinger-Rapport and Y. Rudy. Regularization of the Inverse Problem in Electrocardiography: A Model Study. Mathematical Biosciences 1988 May;89:79-118. PMID: 9214798

L. Widman, J. Liebman, C.W. Thomas, R. Fraenkel, and Y. Rudy. Electrocardiographic Body Surface Potential Maps of the QRS and T of Normal Young Adults – Qualitative Description and Selected Quantifications. J Electrocardiology. 1988 Apr;21(2):121-36. PMID: 3397696

J.N. Amoore and Y. Rudy. The Effect of Variations of Ventricular Volume on the Electrocardiogram. A Comparison of Two Models. J Electrocardiology. 1988 Apr;21(2):154-60. PMID: 3397698

Y. Rudy and B.J. Messinger-Rapport. The Inverse Problem in Electrocardiography: Solutions in terms of Epicardial Potentials. CRC Critical Reviews in Biomedical Engineering. 1988;16(3):215-68. PMID: 3064971

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1987

Y. Rudy and W. Quan. A Model Study of the Effects of the Discrete Cellular Structure on Electrical Propagation in Cardiac Tissue. Circ Res 1987 Dec;61:815-823. PMID: 3677338

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1986

B.J. Messinger-Rapport and Y. Rudy. The Inverse Problem in Electrocardiography: A Model Study of the Effects of Geometry and Conductivity Parameters on the Reconstruction of Epicardial Potentials. IEEE Trans Biomed Eng BME. 1986 Jul;33(7):667-76. PMID: 3733124

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1985

B.J. Messinger-Rapport and Y. Rudy. Effects of the Torso Boundary and Internal Conductivity Interfaces in Electrocardiography: An Evaluation of the ‘Infinite Medium’ Approximation. Bulletin of Mathematical Biology. 1985;47(5):685-94. PMID: 4084698

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1984

J. Liebman, Y. Rudy, P. Diaz, C.W. Thomas, and R. Plonsey. The Spectrum of Right Bundle Branch Block as Manifested in Electrocardiographic Body Surface Potential Maps. J Electrocardiology. 1984 Oct;17(4):329-46. PMID: 6502050

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1983

P. Diaz, Y. Rudy, and R. Plonsey. A Model Study of the Effect of the Intercalated Discs on Discontinuous Propagation in Cardiac Muscle. Advances in Experimental Medicine and Biology. 1983;161:79-89. PMID: 6869084

P. Diaz, Y. Rudy, and R. Plonsey. The Intercalated Discs as a Cause for Discontinuous Propagation in Cardiac Muscle: A Theoretical Simulation. Annals of Biomedical Engineering. 1983;11(3-4):177-89. PMID: 6670783

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1982

Y. Rudy, R. Wood, R. Plonsey, and J. Liebman. The Effect of High Lung Conductivity on ECG Potentials: Results Obtained from Human Subjects Undergoing Bronchopulmonary Lavage. Circulation. 1982;65:440-445. PMID: 7055865

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1981

J. Liebman, C. Thomas, Y. Rudy, and R. Plonsey. Electrocardiographic Body Surface Potential Maps of the QRS of Normal ChildrenJ Electrocardiol. 1981 Jul;14(3):249-60.. PMID: 7264502

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1980

Y. Rudy and R. Plonsey. A Comparison of Volume Conductor and Source Geometry Effects on Body Surface and Epicardial Potentials. Circ Res. 1980 Feb;46(2):283-91.. PMID: 6444278

R. Plonsey and Y. Rudy. Electrocardiogram Sources in a 2-Dimensional Anisotropic Activation Model. Med Biol Eng Comput. 1980 Jan;18(1):87-94. PMID: 7382595

Y. Rudy and R. Plonsey. Comments on the Effect of Variations in the Size of the Heart on the Magnitude of ECG PotentialsJ Electrocardiol. 1980;13(1):79-82. PMID: 6444658

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1979

Y. Rudy and R. Plonsey. The Eccentric Spheres Model as the Basis for a Study of the Role of Geometry and Inhomogeneities in Electrocardiography. IEEE Trans Biomed Eng. 1979 Jul;26(7):392-9. PMID: 457171

Y. Rudy, R. Plonsey, and J. Liebman. The Effects of Variations in Conductivity and Geometrical Parameters on the Electrocardiogram, Utilizing an Eccentric Spheres Model. Circ Res. 1979 Jan;44(1):104-11. PMID: 758226

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1978

Y. Rudy and R.Plonsey. A note on the Brody-Effect. J Electrocardiol. 1978 Jan;11(1):87-90. PMID: 621462

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