Chronological List of Cardiac Excitation & Arrhythmia Publications in Refereed Journals

(Link to MyNCBI Bibiliography)


Y. Rudy. In Silico Pipeline for Drug Cardiotoxicity Assessment. Circ Res. 2020 Apr 10;126(8):965-967. doi: 10.1161/CIRCRESAHA.120.316901. Epub 2020 Apr 9. PMID: 32271685

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J. Xu, Y. Rudy. Effects of β-subunit on gating of a potassium ion channel: Molecular simulations of cardiac IKs activation. J Mol Cell Cardiol. 2018 Nov;124:35-44. doi: 10.1016/j.yjmcc.2018.10.003. Epub 2018 Oct 4. PMCID: PMC6265052

S. Ramasubramanian, Y. Rudy. The Structural Basis of IKs Ion-Channel Activation: Mechanistic Insights from Molecular Simulations. Biophys J. 2018 Jun;114(11):2584-2594. doi: 10.1016/j.bpj.2018.04.023. PMCID: PMC29874609

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H.C. Lee, Y. Rudy, H. Liang, C.C. Chen, C.H. Luo, S.H. Sheu, J. Cui. Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets – Insights from Modeling. J Med Biol Eng. 2017 Oct;37(5):780-789. PMCID: PMC5714284

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A. Nekouzadeh, Y. Rudy. Conformational changes of an ion-channel during gating and emerging electrophysiologic properties: Application of a computational approach to cardiac Kv7.1. Prog Biophys Mol Biol. 2016 Jan;120(1-3):18-27. 2015.12.014. Epub 2015 Dec 30. PMID: 26743208; PMCID: PMC4955398

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D. Jeyaraj, X. Wan, E.Ficker, J.E. Stelzer, I. Deschenes, H. Liu, L. Wilson, K. Decker, T. Said, M. Jain, Y. Rudy, D. Rosenbaum. Ionic bases for electrical remodeling of the canine cardiac ventricle. Am J Physiol Heart Circ Physiol. August 2013; Volume 305 no. H410-H419DOI: 10.1152/ajpheart.00213.2013. PMCID: PMC3742876

J. Heijman, A. Zaza, D.M. Johnson, Y. Rudy, R.L.M. Peeters, P.G.A. Volders, R.L. Westra. Determinants of Beat-to-Beat Variability of Repolarization Duration in the Canine Ventricular Myocyte: a Computational Analysis. PLoS Computational Biology. August 2013; Volume 9, Issue 8, e1003202. PMCID: PMC3749940

H.C. Lee, Y. Rudy, P.Y. Chen, S.H. Sheu, J.G. Chang, J. Cui. Modulation of KCNQ1 Alternative Splicing Regulates Cardiac IKs Currents and Action Potential Repolarization. Heart Rhythm. 2013 Aug;10(8):1220-1228. PMCID: PMC3771516

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Livshitz L, Acsai K, Antoons G, Sipido K, Rudy Y. Data-Based Theoretical Identification of Subcellular Calcium Compartments and Estimation of Calcium Dynamics in Cardiac Myocytes. J Physiol. 2012 Sep 15;590(18):4423-46. doi: 10.1113/jphysiol.2012.228791. Epub 2012 Apr 30. PMCID: PMC3477750

T. O’Hara, Y. Rudy. Quantitative Comparison of Cardiac Ventricular Myocyte Electrophysiology and Response to Drugs in Human and Non-Human Species. Am J Physiol Heart Circ Physiol. 2012 Mar 1;302(5):H1023-30. doi: 10.1152/ajpheart.00785.2011. Epub 2011 Dec 9. PMID: 22159993; PMCID: PMC3311457.

T. O’Hara,Y. Rudy. Arrhythmia Formation in Subclinical (“Silent”) Long QT Syndrome Requires Multiple Insults: Quantitative Mechanistic Study Using the KCNQ1 Mutation Q357R as Example. Heart Rhythm. 2012 Feb;9(2):275-82. doi: 10.1016/j.hrthm.2011.09.066. Epub 2011 Sep 25.. PMCID: PMC3443981

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A. Nekouzadeh, Y. Rudy. Three Residue Loop Closure in Proteins: A New Kinematic Method Reveals a Locus of Connected Loop Conformations. J Comput Chem. 2011 Sep;32(12):2515-25. doi: 10.1002/jcc.21812. PMCID: PMC4154380

P. Li, Y. Rudy. A Model of Canine Purkinje Cell Electrophysiology and Ca2+ Cycling: Rate Dependence, Triggered Activity and Comparison to Ventricular Myocyte. Circ Res. 2011 Jun 24;109(1):71-9. (Issue Highlight). PMCID: PMC3143030

N. Gaur, Y. Rudy. Multiscale modeling of Ca cycling in cardiac ventricular myocyte: Macroscopic consequences of microscopic dyadic function. Biophys J. 2011 Jun 22;100(12):2904-12. PMCID: PMC3123916

A. Nekouzadeh, Y. Rudy. Continuum Molecular Simulation of Large Conformational Changes during Ion-Channel Gating. PLoS ONE. 2011;6(5):e20186. doi: 10.1371/journal.pone.0020186. Epub 2011 May 20. PMCID: PMC3098872

K. Acsai, G. Antoons, L. Livshitz, Y. Rudy, K. R. Sipido. Microdomain [Ca2+] near ryanodine receptors as reported by L-type Ca2+ and Na/Ca exchange currents. J Phsiol. 2011 May 15;589(Pt 10):2569-83. PMCID: PMC3115826

T.J. O’Hara, L. Virág, A. Varró, Y. Rudy. Simulation of the undiseased human cardiac ventricular action potential: Model formulation and experimental validation. PLoS Comput Biol. 2011 May;7(5):e1002061. PMCID: PMC3102752

J. Heijman, P.G.A. Volders, R.L. Westra, Y. Rudy. Local control of β-adrenergic stimulation: Effects on ventricular myocyte electrophysiology and Ca2+-transient. J Mol Cell Cardiol. 2011 May;50(5):863-71. PMCID: PMC3075371

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K.F. Decker, Y. Rudy. Ionic Mechanisms of Electrophysiological Heterogeneity and Conduction Block in the Infarct Border Zone. Am J Physiol Heart Circ Physiol. 2010 Nov;299(5):H1588-97. PMCID: PMC2993197

J. R. Silva, Y. Rudy. Multi-scale electrophysiology modeling: from atom to organ. J. Gen. Physiol. 2010 Jun;135(6):575-81. PMCID: PMC2888060

D. Wu, K. Delaloye, M. Zaydman, A. Nekouzadeh, Y. Rudy, J. Cui. State-dependent electrostatic interactions of S4 arginines with E1 in S2 during Kv7.1 activation. J. Gen. Physiol. 2010 Jun;135(6):595-606. PMCID: PMC2888051

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N. Gaur, Y. Rudy, L. Hool. Contributions of ion-channel currents to ventricular action potential changes and induction of early afterdepolarizations during acute hypoxia. Circ Res. 2009 Dec 4;105(12):1196-203. doi: 10.1161/CIRCRESAHA.109.202267. Epub 2009 Oct 29. PMCID: PMC2826175

L. Livshitz, Y. Rudy. Uniqueness and Stability of Action Potential Models during Rest, Pacing, and Conduction Using Problem-Solving Environment. Biophys J. 2009 Sep 2;97(5):1265-76. doi: 10.1016/j.bpj.2009.05.062. PMCID: PMC2749757

J.R. Silva, H. Pan, D. Wu, A. Nekouzadeh, K. Decker, J. Cui, N. A. Baker, D. Sept, Y. Rudy. A Multiscale Model Linking Ion-Channel Molecular Dynamics and Electrostatics to the Cardiac Action Potential. Proc Natl Acad Sci USA (PNAS). 2009 Jul 7;106(27):11102-6. PMCID: PMC2700153

K. F. Decker, J. Heijman, J.R. Silva, T. J. Hund, Y. Rudy. Properties and Ionic Mechanisms of Action Potential Adaptation, Restitution and Accommodation in Canine Epicardium. Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1017-26. doi: 10.1152/ajpheart.01216.2008. Epub 2009 Jan 23. PMCID: PMC2670702

M. Haissaguerre, JJ Schott, F Sacher, G Lousouran, R Weerasooriya, V Probst, M Horlitz,R Liersch, S LeScouarnec, M Hocini, P Bordachar, P Jais, A Wilde, C Nichols, Y Rudy, H LeMarec. Ventricular fibrillation with prominent early repolarization changes associated to KCNJ8/KATP channel mutation. J Cardiovasc Electrophysiol. 2009 Jan;20(1):93-8. doi: 10.1111/j.1540-8167.2008.01326.x. PMID: 19120683

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A. Nekouzadeh, J. Silva, Y. Rudy. Modeling subunit cooperativity in opening of tetrameric ion channels. Biophys J. 2008 Oct;95(7):3510-20. doi: 10.1529/biophysj.108.136721. Epub 2008 Jul 11. PMCID: PMC2547442

H Sale, J Yang, TJ O’Hara, DJ Tester, P Phartiyal, JQ He, Y Rudy, MJ Ackerman, GA Robertson. Physiological properties of hERG 1a/1b heteromeric currents and hERG 1b-specific mutation associated with long-QT syndrome. Circ Res. 2008 Sep 26;103(7):e81-95. doi: 10.1161/CIRCRESAHA.108.185249. Epub 2008 Sep 5. PMCID: PMC2761010

Y. Rudy, M.J. Ackerman, D. M. Bers, C. E. Clancy, S. R. Houser, B. London, A. D. McCulloch, D. A. Przywara, R. L. Rasmusson, R. J. Solaro, N. A. Trayanova, D. R. Van Wagoner, A. Varró, J. N. Weiss, D. A. Lathrop. Systems approach to understanding electromechanical activity in the human heart: a national heart, lung, and blood institute workshop summary. Circulation. 2008 Sep 9;118(11):1202-11. doi: 10.1161/CIRCULATIONAHA.108.772715. PMCID: PMC2908516

T.J. Hund, K.F. Decker, E. Kanter, P.J. Mohler, P.A. Boyden, R.B. Schuessler, K.A. Yamada, Y. Rudy. Role of activated CaMKII in abnormal calcium homeostasis and INa remodeling after myocardial infarction: Insights from mathematical modeling. J Mol Cell Cardiol. 2008 Sep;45(3):420-8. doi: 10.1016/j.yjmcc.2008.06.007. Epub 2008 Jun 28. PMCID: PMC2587155

M. Bebarova, T. O’Hara, J.L.M.C. Geelen, R.J. Jongbloed, C. Timmermans, Y.H. Arens, L.M. Rodriguez, Y. Rudy, P.G. Volders. Subepicardial phase-0 block and discontinuous transmural conduction underlie right-precordial ST-segment elevation by a SCN5A loss-of-function mutation. Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H48-58. PMCID: PMC2494753

Y. Rudy. Molecular Basis of Cardiac Action Potential Repolarization. Ann N Y Acad Sci. 2008 Mar;1123:113-8. doi: 10.1196/annals.1420.013. PMID: 18375583

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A. Nekouzadeh, Y. Rudy. Statistical Properties of Ion Channel records: II. Estimation from the Macroscopic Current. Math Biosci. 2007 Nov;210(1):315-34. Epub 2007 May 4. PMCID: PMC2151058

A. Nekouzadeh, Y. Rudy. Statistical Properties of Ion Channel records: I. Relationship to the Macroscopic Current. Math Biosci. 2007 Nov;210(1):291-314. Epub 2007 May 4. PMCID: PMC2121577

Y. Rudy. Modeling the Molecular Basis of Cardiac Repolarization. Europace. 2007 Nov;9 Suppl 6:vi17-9. PMID: 17959688

C. Clancy, Z.I. Zhu, Y. Rudy. Pharmacogenetics and Anti-arrhythmic Drug Therapy: A Theoretical Investigation. Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H66-75. Epub 2006 Sep 22.PMCID: PMC2034498

G. Faber, Y. Rudy. Calsequestrin Mutation and Catecholaminergic Polymorphic Ventricular Tachycardia: A Simulation Study of Cellular Mechanism. Cardiovasc Res. 2007 Jul 1;75(1):79-88. Epub 2007 Apr 21. PMCID: PMC2030636

L. Livshitz, Y. Rudy. Regulation of Ca2+ and Electrical Alternans in Cardiac Myocytes: Role of CaMKII and Repolarizing Currents. Am J Physiol Heart Circ Physiol. 2007 Jun;292(6):H2854-66. Epub 2007 Feb 2. PMCID: PMC2274911

G.M. Faber, J. Silva, L. Livshitz, Y. Rudy. Kinetic Properties of the Cardiac L-type Ca2+ Channel and its Role in Myocyte Electrophysiology: A Theoretical Investigation. Biophys J. 2007 Mar 1;92(5):1522-43. Epub 2006 Dec 8. PMCID: PMC1796810

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Y. Rudy, J.R. Silva. Computational Biology in the Study of Cardiac Ion Channels and Cell Electrophysiology. Q Rev Biophys. 2006 Feb; 39(1): 57–116. PMCID: PMC1994938

Y. Rudy. Modeling and Imaging Cardiac Repolarization Abnormalities. J Intern Med. 2006 Jan;259(1): 91–106. PMCID: PMC1865512

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Y. Rudy. Lessons Learned about Slow Discontinuous Conduction from Models of Impulse Propagation. J Electrocardiol. 2005 Oct;38:52-54. PMID: 16226074

J. Silva, Y. Rudy. Subunit Interaction Determines IKs Participation in Cardiac Repolarization and Repolarization reserve. Circulation. 2005 Sep;112:1384-1391. PMCID: PMC1820744

L. Livshitz, K. Decker, G. Faber, T. O’Hara, J. Silva, Y. Rudy. Comments on a Model for Human Ventricular Tissue. Am J Physiol Heart Circ Physiol. 2005 Jan;288:H453- H454 (letter). PMID: 15598875

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T. O’Hara, K. Decker, G. Faber, L. Livshitz, J. Silva, Y. Rudy. Comments on: Role of Individual Ionic Current Systems in Ventricular Cells Hypothesized by Model Study. Jpn J Physiol. 2004 Oct;54:505-508 (letter). PMID: 15667675

T.J. Hund, Y. Rudy. Rate Dependence and Regulation of Action Potential and Calcium Transient in a Canine Cardiac Ventricular Cell Model. Circulation. 2004 Oct;110:3168-3174. PMCID: PMC1851913

Y. Rudy. From Genetics to Cellular Function Using Computational Biology. Annals N.Y. Academy of Science. 2004 May;1015:261-270. PMID: 15201166

Y. Rudy. Genetic Defects, Ionic Currents and Electrocardiographic Alterations. Annals of Medicine. 2004;36:15-21. PMID: 15176419

A.G. Kleber, Y. Rudy. Basic Mechanisms of Cardiac Impulse Propagation and Reentrant Arrhythmias. Physiological Reviews. 2004 Apr;84:431-488. PMID: 15044680

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S.P. Thomas, J.P. Kucera, L. Bircher-Lehman, Y. Rudy , J.E. Saffitz, A.G. Kleber. Impulse Propagation in Synthetic Strands of Neonatal Cardiac Myocytes with Genetically Reduced Levels of Connexin43. Circulation Research. 2003 May;92:1209-1216. PMCID: PMC2242733

J. Silva, Y. Rudy. Pacemaking Activity in Ventricular Myocytes Under Downregulation of Ik1: A Study of Mechanism. Circulation Research. 2003 Jan;92:261-263. PMCID: PMC1890031

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J.P. Kucera, S. Rohr, Y. Rudy. Localization of Sodium Channels in Intercalated Discs Modulates Cardiac Conduction. Circulation Research. 2002 Nov;91:1176-1182. PMCID: PMC1888562

C.E. Clancy, Y. Rudy. A Na+ Channel Mutation that Causes Both Brugada and Long QT Syndrome Phenotypes: A Simulation Study of Mechanism. Circulation. 2002 Mar 12;105:1208-1213. PMCID: PMC199727

K. Gima, Y. Rudy. Ionic Current Basis of Electrocardiographic Waveforms: A Model Study. Circulation Research. 2002 Mar;90:889-896. PMCID: PMC1847799

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T.J. Hund, J.P. Kucera, N.F. Otani, Y. Rudy. Ionic Charge Conservation and Long – Term Steady State in the Luo-Rudy Dynamic Cell Model. Biophys J. 2001 Dec;81:3324-3331. PMCID: PMC1301789

Y. Rudy, together with other 23 members of the Sicilian Gambit on Cardiac Arrhythmia, “New Approaches to Antiarrhythmic Therapy: Emerging Therapeutic Applications of the Cell Biology of Cardiac Arrhythmias”, Part II. Circulation 2001 Dec;104:2990-2994. Co-Published in European Heart Journal, and Cardiovascular Research. PMID: 11739317

Y. Rudy, together with other 23 members of the Sicilian Gambit on Cardiac Arrhythmia. New Approaches to Antiarrhythmic Therapy: Emerging Therapeutic Applications of the Cell Biology of Cardiac Arrhythmias”, Part I. Circulation 2001 Dec;104:2865-2873. Co-Published in European Heart Journal, and Cardiovascular Research. PMID: 11733408

J.P. Kucera, Y. Rudy. Mechanistic Insights into Very Slow Conduction in Branching Cardiac Tissue: A Model Study. Circ Res 2001 Oct;89:799-806. PMID: 11679410

Y. Rudy. The Ionic Mechanisms of Conduction in Cardiac Tissue. J Electrocardiology. 2001 Oct;34:65-68. PMID: 11781938

D. Nuyens, M. Stengl, S. Dugarmaa, T. Rossenbacker, V. Compernolle, Y. Rudy, J.F. Smits, W. Flameng, C.E. Clancy, L. Moons, M.A. Vos, M. Dewerchin, K. Benndorf, D. Collen, E. Carmeliet, P. Carmeliet. Abrupt Rate Accelerations or Premature Beats Cause Life Threatening Arrhythmias in Mice with Long-QT3 Syndrome. Nature Medicine. 2001 Sep; 7:1021-1027. PMID: 11533705

D. Noble, Y. Rudy. Models of Cardiac Ventricular Action Potentials: Iterative Interaction Between Experiment and Simulation. Philosophical Transactions Royal Society (London). 2001 Jun;359:1127-1142.

C. E. Clancy, Y. Rudy. Cellular Consequences of HERG Mutations in the Long QT Syndrome: Precursors to Sudden Cardiac Death. Cardiovascular Research. 2001 May;50:301-313. PMID: 11334834

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P.C. Viswanathan, Y. Rudy. Cellular Arrhythmogenic Effects of the Congenital and Acquired Long QT Syndrome in the Heterogeneous Myocardium. Circulation. 2000 Mar;101:1192-1198. PMID: 10715268

Y. Wang, Y. Rudy. Action Potential Propagation in Inhomogeneous Cardiac Tissue: Safety Factor Considerations and Ionic Mechanism. Am J Physiol (Heart). 2000 Apr;278:H1019- H1029. PMID: 10749693

G.M. Faber, Y. Rudy. Action Potential and Contractility Changes in [Na+]i Overloaded Cardiac Myocytes: A Simulation Study. Biophys J . 2000 May; 78:2392-2404. PMCID: PMC1300828

Y. Rudy. From Genome to Physiome: Integrative Models of Cardiac Excitation. Annals of Biomedical Engineering. 2000 Aug;28:945-950. PMID: 11144679

T.J. Hund, N.F. Otani, Y. Rudy. The Dynamics of Action Potential Head-Tail Interaction During Reentry in Cardiac Tissue: Ionic Mechanisms. Am J Physiol (Heart). 2000 Oct;279:H1869-H1879. PMID: 11009475

E. Ficker, D. Thomas, P.C. Viswanathan, A. T. Dennis, S. G. Priori, C. Napolitano, M. Memmi, B.A. Wible, E. S. Kaufman, S. Iyengar, P. J. Schwartz, Y. Rudy, A.M. Brown. Novel Characteristics of a Misprocessed Mutant HERG Channel Linked to Hereditary Long QT Syndrome. Am J Physiol (Heart). 2000 Oct;279:H1748-H1756. PMID: 11009462

T.J. Hund, Y. Rudy. Determinants of Excitability in Cardiac Myocytes: Mechanistic Investigation of Memory Effect. Biophys J. 2000 Dec;79:3095-3104. PMCID: PMC1301186

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C. E. Clancy, Y. Rudy. Linking a genetic defect to its cellular phenotype in a cardiac arrhythmia. Nature. 1999 Aug;400:566-569. PMID: 10448858

P.C. Viswanathan, R.M. Shaw, Y. Rudy. Effects of Ikr and Iks Heterogeneity on Action Potential Duration and its Rate-Dependence: A Simulation Study. Circulation. 1999 May;99:2466-2474. PMID: 10318671

P.C. Viswanathan, Y. Rudy. Pause Induced Early Afterdepolarizations in the Long QT Syndrome: A Simulation Study. Cardiovascular Research. 1999 May;42:530-542. PMID: 10533588

S.G. Priori, J. Barhanin, R.N.W. Hauer, W. Haverkamp, H.J. Jongsma, A.G. Kleber, W.J. McKenna, D.M. Roden, Y. Rudy, K. Schwartz, P.J. Schwartz, J.A. Towbin, A.M. Wilde. Genetic and Molecular Basis of Cardiac Arrhythmias, Parts I and II. Circulation. 1999 Feb;99:518-528. Also published in Eur Heart J. (1999) 20, 174-195. PMID: 9927398

S.G. Priori, J. Barhanin, R.N.W. Hauer, W. Haverkamp, H.J. Jongsma, A.G. Kleber, W.J. McKenna, D.M. Roden, Y. Rudy, K. Schwartz, P.J. Schwartz, J.A. Towbin, A.M. Wilde. Genetic and Molecular Basis of Cardiac Arrhythmias, Part III. Circulation. 1999 Feb;99:674-681. Also published in Eur Heart J. (1999) 20, 174-195. PMID: 9950666

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R.M. Shaw and Y. Rudy. Ionic Mechanisms of Propagation in Cardiac Tissue: Roles of the Sodium and L-Type Calcium Currents During Reduced Excitability and Decreased Gap-Junction Coupling. Circ Res. 1997 Nov;81:727-741. PMID: 9351447

K.R. Laurita, S.D. Girouard, Y. Rudy, D.S. Rosenbaum. Role of Passive Electrical Properties During Action Potential Restitution in the Intact Heart. Am J. Physiol. 1997 Sep;273:H1205-H1214. PMID: 9321808

R.M. Shaw and Y. Rudy. Electrophysiologic Effects of Acute Myocardial Ischemia: A Theoretical Study of Altered Cell Excitability and Action Potential Duration. Cardiovascular Research. 1997 Aug;35:256-272. PMID: 9349389

Y. Rudy, and R.M. Shaw. Cardiac Excitation: An Interactive Process of Ion Channels and Gap Junctions. Adv Exp Med Biol. 1997; 430: 269-280. PMID: 9330736

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J. Zeng, K. R. Laurita, D. S. Rosenbaum, and Y. Rudy. Two Components of the Delayed Rectifier K+ Current in Ventricular Myocytes of the Guinea Pig Type: Theoretical Formulation and their Role in Repolarization. Circulation Research. 1995 Jul;77:1-13. PMID: 7788872

Y. Rudy. Reentry: Insights from Theoretical Simulations in a Fixed Pathway. J Cardiovascular Electrophysiology. 1995 Apr;6:294-312. PMID: 7544193

Y. Rudy. Model Studies of Cellular Excitation. Adv Exp Med Biol. 1995; 382: 67-77. PMID: 8540415

J. Zeng and Y. Rudy. Early Afterdepolarizations in Cardiac Myocytes: Mechanism and Rate Dependence. Biophys J. 1995 Mar;68:949-964. PMCID: PMC1281819

R.M. Shaw and Y. Rudy. The Vulnerable Window for Unidirectional Block in Cardiac Tissue: Characterization and Dependence on Membrane Excitability and Cellular Coupling. J Cardiovascular Electrophysiology. 1995 Feb;6:115-131. PMID: 7780627

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S. Niwano, J.Ortiz, H. Abe, X. Gonzalez, Y. Rudy, and A.L. Waldo. Characterization of the excitable gap in a functionally determined reentrant circuit. Circulation. 1994 Oct;90:1997-2014. PMID: 7522990

D.W. Whalley, D.J. Wendt, C.F. Starmer, Y. Rudy, and A.O. Grant. Voltage- Independent Effects of Extracellular K+ on the Na+ Current and Phase 0 of the Action Potential in Isolated Cardiac Myocytes. Circulation Research 1994 Sep;75:491-502. PMID: 8062422

C. Luo and Y. Rudy. A Dynamic Model of the Cardiac Ventricular Action Potential: II. Afterdepolarizations, Triggered Activity and Potentiation. Circulation Research. 1994 Jun;74:1097-1113. PMID:7514510

C. Luo and Y. Rudy. A Dynamic Model of the Cardiac Ventricular Action Potential: I. Simulations of Ionic Currents and Concentration Changes. Circulation Research. 1994 Jun;74:1071-1096. PMID:7514509

J. Ortiz, A. Nozaki, A. Shimizu, Y. Rudy, and A.Waldo. Mechanism of Interruption of Atrial Flutter by Moricizine: Electrophysiological and Multiplexing Studies in the Canine Sterile Pericarditis Model of Atrial Flutter. Circulation. 1994 Jun;89(6):2860-9. PMID: 8205702

F. Dexter, Y. Rudy, and G.M. Saidel. Mathematical Model of Acetylcholine Kinetics in Neuroeffector Junctions. Am J Physiol. 1994 Jan;266(1 Pt 2):H298-309. PMID: 8304512

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D. Khoury and Y. Rudy. A Model Study of Volume Conductor Effects on Endocardial and Intracavitary Potentials. Circulation Research. 1992 Sep;71:511-525. PMID: 1499104

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W. Quan and Y. Rudy. Termination of Reentrant Propagation by a Single Stimulus – A Model Study. PACE. 1991 Nov;14:1700-1706. PMID:1721161

Y. Rudy and W. Quan. Propagation Delays Across Gap Junctions and their Reflection in Extracellular Potentials: a Simulation Study. J Cardiovascular Electrophysiology. 1991 Aug;2:299-315.

C. Luo and Y. Rudy. A Model of the Ventricular Cardiac Action Potential: Depolarization, Repolarization and their Interaction. Circulation Research. 1991 Jun;68:1501-1526. PMID: 1709839

F. Dexter, Y. Rudy, M.N. Levy, and E.N. Bruce. Mathematical Model of Cellular Basis for the Respiratory Sinus Arrhythmia. J Theor Biol. 1991 May;150:157-173. PMID: 1890853

A. Shimizu, A. Nozaki, Y. Rudyand A.L. Waldo. Onset of Induced Atrial Flutter in the Canine Pericarditis Model. J Amer College Cardiol. 1991 Apr;17: 1223-1234. PMID: 2007723

J. Liebman, B. Olshansky, A. Zeno, A. Geha, Y. Rudy, W. Henthorn, M. Cohen, and A.L. Waldo. Electrocardiographic Body Surface Potential Mapping in the Wolff – Parkinson -White Syndrome: Non-invasive Determination of the Ventricular Insertion Sites of AV Connections. Circulation. 1991 Mar;83:886-901. PMID: 1890853

A. Shimizu, A. Nozaki, Y. Rudy and A.L. Waldo. Multiplexing Studies of the Effects of Rapid Atrial Pacing on the Area of Slow Conduction During Atrial Flutter in the Canine Pericarditis Model. Circulation. 1991 Mar;83:983-994. PMID: 1999046

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W. Quan and Y. Rudy. Unidirectional Block and Reentry of Cardiac Excitation-A Model Study. Circulation Research. 1990 Feb;66:367-382. PMID: 2297808

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F. Dexter, G.M. Saidel, and Y. Rudy. Simulation of the diffusion of Acetylcholine in the Neuroeffector Junctions of the Sinus Node. J Theo Boils. 1989 Dec 19;141(4):505-14. PMID: 2630802

F. Dexter, M.N. Levy, Y. Rudy. Mathematical Model of the Changes in Heart Rate Elicited by Vagal Stimulation. Circulation Research. 1989 Nov;65:1330-1339. PMID: 2805246

F. Dexter, Y. Rudy, M.N. Levy. Muscarinic Autoreceptors do not Modulate Kinetics of Acetylcholine Release in Hearts. Am J Physiol. 1989 Apr;256(4 Pt 2):H1073-8. PMID: 2705550

F. Dexter, G.M. Saidel, M.N. Levy, and Y. Rudy. Mathematical Model of the Dependence of Heart Rate on the Tissue Concentration of Acetylcholine. Am J Physiol. 1989 Feb;256(2 Pt 2):H520-6. PMID: 2916685

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Y. Rudy and W. Quan. A Model Study of the Effects of the Discrete Cellular Structure on Electrical Propagation in Cardiac Tissue. Circ Res 1987 Dec;61:815-823. PMID: 3677338

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P. Diaz, Y. Rudy, and R. Plonsey. A Model Study of the Effect of the Intercalated Discs on Discontinuous Propagation in Cardiac Muscle. Advances in Experimental Medicine and Biology. 1983;161:79-89. PMID: 6869084

P. Diaz, Y. Rudy, and R. Plonsey. The Intercalated Discs as a Cause for Discontinuous Propagation in Cardiac Muscle: A Theoretical Simulation. Annals of Biomedical Engineering. 1983;11(3-4):177-89. PMID: 6670783

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Y. Rudy and R. Plonsey. A Comparison of Volume Conductor and Source Geometry Effects on Body Surface and Epicardial Potentials. Circ Res. 1980 Feb;46(2):283-91.. PMID: 6444278

R. Plonsey and Y. Rudy. Electrocardiogram Sources in a 2-Dimensional Anisotropic Activation Model. Med Biol Eng Comput. 1980 Jan;18(1):87-94. PMID: 7382595

Y. Rudy and R. Plonsey. Comments on the Effect of Variations in the Size of the Heart on the Magnitude of ECG Potentials. J Electrocardiol. 1980;13(1):79-82. PMID: 6444658

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Y. Rudy and R. Plonsey. The Eccentric Spheres Model as the Basis for a Study of the Role of Geometry and Inhomogeneities in Electrocardiography. IEEE Trans Biomed Eng. 1979 Jul;26(7):392-9. PMID: 457171

Y. Rudy, R. Plonsey, and J. Liebman. The Effects of Variations in Conductivity and Geometrical Parameters on the Electrocardiogram, Utilizing an Eccentric Spheres Model. Circ Res. 1979 Jan;44(1):104-11. PMID: 758226

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Y. Rudy and R.Plonsey. A note on the Brody-Effect. J Electrocardiol. 1978 Jan;11(1):87-90. PMID: 621462

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