Rudy lab conducts first study of electromechanics of healthy, living human hearts. While there have been numerous studies of abnormalities in the human heart, there have not been studies of the electromechanics of healthy adult hearts — until now.
A New Noninvasive Treatment Based on Electrocardiographic Imaging (ECGI) was developed in Dr. Yoram Rudy’s laboratory. The treatment is offered at Washington University in St. Louis and at the Cleveland Clinic.
The CardioInsight ECGI system was cleared by the FDA. After 30 years of development and validation in Professor Yoram Rudy’s laboratory, he hopes to see ECGI in clinical use in hospitals, helping to treat cardiac patients.
While at Case Western Reserve University, Professor Yoram Rudy had the idea for a game-changing cardiac monitoring device–a vest filled with more than 200 sensors that could detect the heart’s electrical activity.
A recent publication in the journal Circulation describes research conducted by Ramya Vijayakumar, a PhD student in the lab. Ramya used a novel noninvasive imaging modality – Electrocardiographic Imaging (ECGI) to study the arrhythmic substrate in the hearts of 25 patients.
Dr. Yoram Rudy was awarded a $1,520,000 four year grant (years 21-24 of the award) from the NIH – National Heart, Lung and Blood Institute for the project titled “Cardiac Excitation and Arrhythmias.”
CardioInsight Technologies, whose technology was initiated by Rudy Lab Alumni Charu Ramanathan and Ping Jia, continues the development of Electrocardiographic Imaging (ECGI) for clinical application.
Dr. Yoram Rudy was awarded a $1,520,000 four year grant (years 28-31 of the award) from the NIH, National Heart, Lung and Blood Institute, for the project “Inverse and Forward Problems in Electrocardiography.”
Yoram Rudy, Fred Saigh distinguished professor and director of the Cardiac Bioelectricity and Arrhythmia Center at Washington University in St Louis, St Louis, USA, talked to Cardiac Rhythm News about the novel imaging technique, electrocardiographic imaging, which was developed in his laboratory.
Study shows a noninvasive, fast way to map the heart’s electrical activity in one heartbeat. This article features Dr. Yoram Rudy, and his lab members Junjie Zhang, Kavit A. Desouza, MD, Ramya Vijayakumar and fellow collaborators.
Yoram Rudy was awarded a $1,900,000 four year grant (years 17-20 of the award) from the National Institutes of Health and a three year $294,621 grant from the National Science Foundation.
Thomas O’Hara was awarded two-year grant from the Predoctoral Fellowship Program of the Midwest Affiliate Research Committee of the American Heart Association for his “Mathematical Model of Human Cardiac Ventricular Action Potential” project.
Dr. Yoram Rudy was awarded a $1,362,285 four year grant, (years 24-27 of a Merit Award to Dr. Rudy) from the NIH, National Heart, Lung and Blood Institute for his Inverse and Forward Problems in Electrocardiography project.
Washington University School of Medicine’s quarterly magazine, Outlook, is published by the Office of Medical Public Affairs. Biomedical Engineering Professor Yoram Rudy’s Lab was featured as the Outlook Winter 2007 cover story.
Yoram Rudy participated in a workshop on Regulation of Transport Phenomena in the Cardiac System. The workshop took place in Antalya, Turkey, September 16-20, 2007.
The paper “Application of the Method of Fundamental Solutions to Potential-based Inverse Electrocardiography” by Yong Wang and Yoram Rudy had been chosen as the Outstanding Original Paper for 2006 in the Annals of Biomedical Engineering. The award carries a prize of $1500 that will be used to support Yong Wang.
Yoram Rudy organized and chaired the workshop “Systems Approach to Understanding Electromechanical Activity in the Human Heart” at the NIH-National Heart, Lung and Blood Institute (Washington D.C., August 20-21, 2007). Participants included 13 leading scientists in cardiac research. They developed a list of recommendations for future research directions and support.
Greg Faber presented an abstract “Calsequestrin Mutation Results in Spontaneous Calcium Release and Delayed Afterdepolarizations in a Model of the Cardiac Ventricular Myocyte” in the American Heart Association Scientific Sessions, Dallas, Nov. 2005.
Dr. Yoram Rudy’s lab developed the first mathematical model of a canine cardiac cell that incorporates a vital calcium regulatory pathway that has implications in life-threatening cardiac arrhythmias, or irregular heartbeats. This article also features members of the Rudy Lab: Thomas Hund, Yong Wang, Leonid Livshitz
Dr. Yoram Rudy, Director of the Cardiac Bioelectricity and Arrhythmia Center (CBAC) at Washington University in St. Louis, has, over the past 20 years, developed a unique method of electrocardiographic imaging (ECGI) that provides a noninvasive and detailed technique for recording electrical activity of the heart.